Xabier
Aguirre Ena
Profesional Investigador
Amaia
Vilas Zornoza
Investigadora hasta 2022
Publicaciones en las que colabora con Amaia Vilas Zornoza (26)
2024
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An atlas of cells in the human tonsil
Immunity, Vol. 57, Núm. 2, pp. 379-399.e18
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Epigenetic-based differentiation therapy for Acute Myeloid Leukemia
Nature Communications, Vol. 15, Núm. 1
2023
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Revealing cell populations catching the early stages of human embryo development in naive pluripotent stem cell cultures
Stem Cell Reports, Vol. 18, Núm. 1, pp. 64-80
2021
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Characterization of complete lncRNAs transcriptome reveals the functional and clinical impact of lncRNAs in multiple myeloma
Leukemia, Vol. 35, Núm. 5, pp. 1438-1450
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Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with in Vivo Efficacy in Multiple Myeloma
Journal of Medicinal Chemistry, Vol. 64, Núm. 6, pp. 3392-3426
2020
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Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma
Genome Research, Vol. 30, Núm. 9, pp. 1217-1227
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Immunogenomic identification and characterization of granulocytic myeloid-derived suppressor cells in multiple myeloma
Blood, Vol. 136, Núm. 2, pp. 199-209
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Re: Inhibition of a G9a/DNMT Network Triggers Immune-Mediated Bladder Cancer Regression
Journal of Urology
2019
2018
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Deregulation of linc-PINT in acute lymphoblastic leukemia is implicated in abnormal proliferation of leukemic cells
Oncotarget, Vol. 9, Núm. 16, pp. 12842-12852
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Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6518-6545
2017
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Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies
Nature Communications, Vol. 8
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Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome
PLoS ONE, Vol. 12, Núm. 12
2016
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Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics
Nature Communications, Vol. 7
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Use of human pharyngeal and palatine tonsils as a reservoir for the analysis of B-cell ontogeny in 10 paired samples
Clinical Otolaryngology, Vol. 41, Núm. 5, pp. 606-611
2012
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Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia
Leukemia, Vol. 26, Núm. 7, pp. 1517-1526
2011
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Deregulation of FGFR1 and CDK6 oncogenic pathways in acute lymphoblastic leukaemia harbouring epigenetic modifications of the MIR9 family
British Journal of Haematology, Vol. 155, Núm. 1, pp. 73-83
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Development and validation of ultra high performance liquid chromatography-mass spectrometry method for LBH589 in mouse plasma and tissues
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Vol. 879, Núm. 30, pp. 3490-3496
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Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in Acute Lymphoblastic Leukemia
PLoS ONE, Vol. 6, Núm. 2
2010
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Epigenetic regulation of the non-canonical Wnt pathway in acute myeloid leukemia
Cancer Science, Vol. 101, Núm. 2, pp. 425-432