Sandra
Hervas Stubbs
Profesional Investigadora
José Luis
Pérez Gracia
Consultor Médico
Publicaciones en las que colabora con José Luis Pérez Gracia (20)
2012
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The HIF-1α hypoxia response in tumor-infi ltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy
Cancer Discovery, Vol. 2, Núm. 7, pp. 608-623
2011
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Agonist anti-CD137 mAb act on tumor endothelial cells to enhance recruitment of activated T lymphocytes
Cancer Research, Vol. 71, Núm. 3, pp. 801-811
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Carcinoma-derived Interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation
PLoS ONE, Vol. 6, Núm. 3
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Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes
PLoS ONE, Vol. 6, Núm. 12
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Direct effects of type I interferons on cells of the immune system
Clinical Cancer Research, Vol. 17, Núm. 9, pp. 2619-2627
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Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients
Journal of Immunology, Vol. 187, Núm. 11, pp. 6130-6142
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Synergistic effects of CTLA-4 blockade with tremelimumab and elimination of regulatory T lymphocytes in vitro and in vivo
International Journal of Cancer, Vol. 129, Núm. 2, pp. 374-386
2010
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Delivery of immunostimulatory monoclonal antibodies by encapsulated hybridoma cells
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 11, pp. 1621-1631
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Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 8, pp. 1223-1233
2009
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Clinical development of combination strategies in immunotherapy: Are we ready for more than one investigational product in an early clinical trial?
Immunotherapy, Vol. 1, Núm. 5, pp. 845-853
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In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb
European Journal of Immunology, Vol. 39, Núm. 9, pp. 2424-2436
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Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes
British Journal of Cancer, Vol. 100, Núm. 7, pp. 1111-1119
2008
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Interleukin-15 liver gene transfer increases the number and function of IKDCs and NK cells
Gene Therapy, Vol. 15, Núm. 7, pp. 473-483
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Multi-layered action mechanisms of CD137 (4-1BB)-targeted immunotherapies
Trends in Pharmacological Sciences, Vol. 29, Núm. 8, pp. 383-390
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Polly Matzinger's "danger model" finds its predicted danger-denoting self moieties
Inmunologia, Vol. 27, Núm. 4, pp. 205-211
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Therapeutic antitumor efficacy of anti-CD137 agonistic monoclonal antibody in mouse models of myeloma
Clinical Cancer Research, Vol. 14, Núm. 21, pp. 6895-6906
2007
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Cellular liaisons of natural killer lymphocytes in immunology and immunotherapy of cancer
Expert Opinion on Biological Therapy, Vol. 7, Núm. 5, pp. 599-615
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The combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFNγ
International Journal of Cancer, Vol. 121, Núm. 6, pp. 1282-1295
2006
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Immunogenic cell death and cross-priming are reaching the clinical immunotherapy arena
Clinical Cancer Research
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Recombinant Adenoviral Vectors Turn on the Type I Interferon System without Inhibition of Transgene Expression and Viral Replication
Molecular Therapy, Vol. 14, Núm. 1, pp. 129-138