María Ujué
Latasa Sada
Investigadora Asociada
Bruno Carlos
Sangro Gómez-Acebo
Catedrático de Universidad
Publications dans lesquelles il/elle collabore avec Bruno Carlos Sangro Gómez-Acebo (14)
2024
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Caspases compromise SLU7 and UPF1 stability and NMD activity during hepatocarcinogenesis
JHEP Reports, Vol. 6, Núm. 8
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Identification of PRMT5 as a therapeutic target in cholangiocarcinoma
Gut
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New insights into the regulation of bile acids synthesis during the early stages of liver regeneration: A human and experimental study
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1870, Núm. 5
2023
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Comprehensive analysis of epigenetic and epitranscriptomic genes’ expression in human NAFLD
Journal of Physiology and Biochemistry, Vol. 79, Núm. 4, pp. 901-924
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Identification and experimental validation of druggable epigenetic targets in hepatoblastoma
Journal of Hepatology, Vol. 79, Núm. 4, pp. 989-1005
2022
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New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming
Journal of Experimental and Clinical Cancer Research, Vol. 41, Núm. 1
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Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures
Gut, Vol. 71, Núm. 6, pp. 1141-1151
2021
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Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma
Hepatology, Vol. 73, Núm. 6, pp. 2380-2396
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Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: Dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis
Gut, Vol. 70, Núm. 2, pp. 388-400
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The splicing regulator SLU7 is required to preserve DNMT1 protein stability and DNA methylation
Nucleic Acids Research, Vol. 49, Núm. 15, pp. 8592-8609
2020
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Pilot multi-omic analysis of human bile from benign and malignant biliary strictures: A machine-learning approach
Cancers, Vol. 12, Núm. 6, pp. 1-30
2019
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Splicing events in the control of genome integrity: Role of SLU7 and truncated SRSF3 proteins
Nucleic Acids Research, Vol. 47, Núm. 7, pp. 3450-3466
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The Epidermal Growth Factor Receptor Ligand Amphiregulin Protects From Cholestatic Liver Injury and Regulates Bile Acids Synthesis
Hepatology, Vol. 69, Núm. 4, pp. 1632-1647
2009
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Wilms' tumor 1 gene expression in hepatocellular carcinoma promotes cell dedifferentiation and resistance to chemotherapy
Cancer Research, Vol. 69, Núm. 4, pp. 1358-1367