Edurne
San José Enériz
Investigadora Asociada
Leire
Garate Iturriagagoitia
Investigadora Colaboradora
Publications by the researcher in collaboration with Leire Garate Iturriagagoitia (29)
2024
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An automated network-based tool to search for metabolic vulnerabilities in cancer
Nature Communications , Vol. 15, Núm. 1
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Epigenetic-based differentiation therapy for Acute Myeloid Leukemia
Nature Communications, Vol. 15, Núm. 1
2021
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Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with in Vivo Efficacy in Multiple Myeloma
Journal of Medicinal Chemistry, Vol. 64, Núm. 6, pp. 3392-3426
2019
2018
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Detailed Exploration around 4-Aminoquinolines Chemical Space to Navigate the Lysine Methyltransferase G9a and DNA Methyltransferase Biological Spaces
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6546-6573
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Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6518-6545
2017
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An in-silico approach to predict and exploit synthetic lethality in cancer metabolism
Nature Communications, Vol. 8, Núm. 1
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In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer
Scientific Reports, Vol. 7, Núm. 1
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Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome
PLoS ONE, Vol. 12, Núm. 12
2012
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Down-regulated expression of hsa-miR-181c in Fanconi anemia patients: Implications in TNFα regulation and proliferation of hematopoietic progenitor cells
Blood, Vol. 119, Núm. 13, pp. 3042-3049
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Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia (Blood (2007) 109, 8 (3462-3469))
Blood
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Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia
Leukemia, Vol. 26, Núm. 7, pp. 1517-1526
2011
2009
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Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia
European Journal of Cancer, Vol. 45, Núm. 10, pp. 1877-1889
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Epigenetic regulation of MicroRNAs in acute lymphoblastic leukemia
Journal of Clinical Oncology, Vol. 27, Núm. 8, pp. 1316-1322
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Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia
Cancer Research, Vol. 69, Núm. 10, pp. 4443-4453
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MicroRNA expression profiling in Imatinib-resistant Chronic Myeloid Leukemia patients without clinically significant ABL1-mutations
Molecular Cancer, Vol. 8, pp. 69
2008
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BCR-ABL1-induced expression of HSPA8 promotes cell survival in chronic myeloid leukaemia
British Journal of Haematology, Vol. 142, Núm. 4, pp. 571-582
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Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth
Molecular Cancer Research, Vol. 6, Núm. 12, pp. 1830-1840
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Methylation status of Wnt signaling pathway genes affects the clinical outcome of Philadelphia-positive acute lymphoblastic leukemia
Cancer Science, Vol. 99, Núm. 9, pp. 1865-1868