
Juan
Dubrot Armendáriz
Profesional Investigador
Publications (56) Juan Dubrot Armendáriz publications
2025
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Leveraging epigenetic alterations in pancreatic ductal adenocarcinoma for clinical applications
Seminars in Cancer Biology, Vol. 109, pp. 101-124
2024
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Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
Immunity, Vol. 57, Núm. 12, pp. 2863-2878.e12
2023
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Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening
Nature Communications, Vol. 14, Núm. 1
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Protocol for in vivo CRISPR screening using selective CRISPR antigen removal lentiviral vectors
STAR Protocols, Vol. 4, Núm. 1
2022
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In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer
Nature Immunology, Vol. 23, Núm. 10, pp. 1495-1506
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Mutant IDH Inhibits IFNg–TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma
Cancer Discovery, Vol. 12, Núm. 3, pp. 812-835
2021
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In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma
Immunity, Vol. 54, Núm. 3, pp. 571-585.e6
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MHC Class II antigen presentation by lymphatic endothelial cells in tumors promotes intratumoral regulatory T cell-suppressive functions
Cancer Immunology Research, Vol. 9, Núm. 7, pp. 748-764
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Macroautophagy in lymphatic endothelial cells inhibits T cell-mediated autoimmunity
Journal of Experimental Medicine, Vol. 218, Núm. 6
2019
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Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
Nature, Vol. 565, Núm. 7737, pp. 43-48
2018
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Absence of MHC-II expression by lymph node stromal cells results in autoimmunity
Life Science Alliance, Vol. 1, Núm. 6
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Dendritic cell migration toward CCL21 gradient requires functional Cx43
Frontiers in Physiology, Vol. 9, Núm. MAR
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Impact of the tumor microenvironment on lymphatic phenotype and function
SWISS MEDICAL WEEKLY
2017
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Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function
PLoS ONE, Vol. 12, Núm. 7
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Pannexin1 links lymphatic function to lipid metabolism and atherosclerosis
Scientific Reports, Vol. 7, Núm. 1
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Shaping of peripheral T cell responses by lymphatic endothelial cells
Frontiers in Immunology, Vol. 7, Núm. JAN
2016
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IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity
Journal of Autoimmunity, Vol. 75, pp. 39-49
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PDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation
Journal of Autoimmunity, Vol. 67, pp. 8-18
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The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells
Immunity, Vol. 45, Núm. 6, pp. 1205-1218
2015
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Fundamental Roles of the Golgi-Associated Toxoplasma Aspartyl Protease, ASP5, at the Host-Parasite Interface
PLoS Pathogens, Vol. 11, Núm. 10