Publications

Juan Dubrot Armendáriz publications

60 results

2026

  1. Inflammatory cytokines induce new cancer dependencies

    Nature Genetics, Vol. 58, Núm. 6, pp. 1353-1367

  2. Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity

    Cancer Cell, Vol. 44, Núm. 5, pp. 995-1011.e12

2025

  1. Computational modeling of metabolism in oncology

    Metabolites as Signals in Immunity and Inflammation (Elsevier), pp. 81-107

  2. In vivo CRISPR screening in head and neck cancer reveals Uchl5 as an immunotherapy target

    Nature Communications , Vol. 16, Núm. 1

  3. Leveraging epigenetic alterations in pancreatic ductal adenocarcinoma for clinical applications

    Seminars in Cancer Biology, Vol. 109, pp. 101-124

2024

  1. Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint

    Immunity, Vol. 57, Núm. 12, pp. 2863-2878.e12

2023

  1. Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening

    Nature Communications, Vol. 14, Núm. 1

  2. Protocol for in vivo CRISPR screening using selective CRISPR antigen removal lentiviral vectors

    STAR Protocols, Vol. 4, Núm. 1

2022

  1. In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer

    Nature Immunology, Vol. 23, Núm. 10, pp. 1495-1506

  2. Mutant IDH Inhibits IFNg–TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma

    Cancer Discovery, Vol. 12, Núm. 3, pp. 812-835

2021

  1. In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma

    Immunity, Vol. 54, Núm. 3, pp. 571-585.e6

  2. MHC Class II antigen presentation by lymphatic endothelial cells in tumors promotes intratumoral regulatory T cell-suppressive functions

    Cancer Immunology Research, Vol. 9, Núm. 7, pp. 748-764

  3. Macroautophagy in lymphatic endothelial cells inhibits T cell-mediated autoimmunity

    Journal of Experimental Medicine, Vol. 218, Núm. 6

2019

  1. Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

    Nature, Vol. 565, Núm. 7737, pp. 43-48

2018

  1. Absence of MHC-II expression by lymph node stromal cells results in autoimmunity

    Life Science Alliance, Vol. 1, Núm. 6

  2. Dendritic cell migration toward CCL21 gradient requires functional Cx43

    Frontiers in Physiology, Vol. 9, Núm. MAR

  3. Impact of the tumor microenvironment on lymphatic phenotype and function

    SWISS MEDICAL WEEKLY

2017

  1. Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function

    PLoS ONE, Vol. 12, Núm. 7

  2. Pannexin1 links lymphatic function to lipid metabolism and atherosclerosis

    Scientific Reports, Vol. 7, Núm. 1

  3. Shaping of peripheral T cell responses by lymphatic endothelial cells

    Frontiers in Immunology, Vol. 7, Núm. JAN