Borja
Sáez Ochoa
Researcher to 2022
Harvard University
Cambridge, Estados UnidosPublications in collaboration with researchers from Harvard University (14)
2021
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tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche
Cell Stem Cell, Vol. 28, Núm. 12, pp. 2090-2103.e9
2020
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Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers
Blood, Vol. 136, Núm. 11, pp. 1303-1316
2019
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Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation
Nature Communications, Vol. 10, Núm. 1
2017
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Harnessing the Biology of Stem Cells' Niche
Biology and Engineering of Stem Cell Niches (Elsevier Inc.), pp. 15-31
2016
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Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells
Cell, Vol. 167, Núm. 5, pp. 1310-1322.e17
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Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin
Nature Biotechnology, Vol. 34, Núm. 7, pp. 738-745
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Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway
Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Núm. 7, pp. 1871-1876
2015
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Parent stem cells can serve as niches for their daughter cells
Nature, Vol. 523, Núm. 7562, pp. 597-601
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Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow
Journal of Experimental Medicine, Vol. 212, Núm. 5, pp. 759-774
2014
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D-cyclins repress apoptosis in hematopoietic cells by controlling death receptor fas and its ligand FasL
Developmental Cell, Vol. 30, Núm. 3, pp. 255-267
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Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning
Blood, Vol. 124, Núm. 19, pp. 2937-2947
2013
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Sox4 Is a Key Oncogenic Target in C/EBPα Mutant Acute Myeloid Leukemia
Cancer Cell, Vol. 24, Núm. 5, pp. 575-588
2011
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AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias
Cell, Vol. 146, Núm. 5, pp. 697-708
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Diabetes impairs hematopoietic stem cell mobilization by altering niche function
Science Translational Medicine, Vol. 3, Núm. 104