Publicaciones (20) Publicaciones de Irati Macaya Erro

2024

  1. RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis

    iScience, Vol. 27, Núm. 4

  2. Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation

    Molecular Cancer, Vol. 23, Núm. 1

2023

  1. Correction: The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer (Molecular Cancer, (2023), 22, 1, (86), 10.1186/s12943-023-01788-w)

    Molecular Cancer

  2. LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth

    Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 29, Núm. 6, pp. 1137-1154

  3. Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer

    Nature Communications, Vol. 14, Núm. 1

  4. The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer

    Molecular Cancer, Vol. 22, Núm. 1

2022

  1. Characterization of KRAS-driven NSCLC cell lines with diverse mutational landscape and assessment of their response to MYC inhibition

    European Journal of Cancer, Vol. 174, pp. S47

  2. Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis

    Cancer Letters, Vol. 529, pp. 70-84

  3. Myosin Vb as a tumor suppressor gene in intestinal cancer

    Oncogene, Vol. 41, Núm. 49, pp. 5279-5288

2021

  1. FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted

    Journal of Hepatology, Vol. 75, Núm. 2, pp. 363-376

2020

  1. Liver Kinase B1 (LKB1) Loss Has its p-ERKs: ERK Inactivation as a Vulnerability in NSCLC With LKB1 Mutations

    Journal of Thoracic Oncology

  2. Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade

    Nature cancer, Vol. 1, Núm. 1, pp. 75-85

2018

  1. Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal cancer

    British Journal of Cancer, Vol. 118, Núm. 1, pp. 106-116

  2. Silencing of adaptor protein SH3BP2 reduces KIT/PDGFRA receptors expression and impairs gastrointestinal stromal tumors growth

    Molecular Oncology, Vol. 12, Núm. 8, pp. 1383-1397

2017

  1. Investigation of the role of tyrosine kinase receptor EPHA3 in colorectal cancer

    Scientific Reports, Vol. 7

  2. Loss of the EPH receptor B6 contributes to colorectal cancer metastasis

    Scientific Reports, Vol. 7

2015

  1. Highly expressed genes in rapidly proliferating tumor cells as new targets for colorectal cancer treatment

    Clinical Cancer Research, Vol. 21, Núm. 16, pp. 3695-3704

  2. Myo5b knockout mice as a model of microvillus inclusion disease

    Scientific Reports, Vol. 5

2014

  1. RHOA inactivation enhances Wnt signalling and promotes colorectal cancer

    Nature Communications, Vol. 5

2013

  1. Brush border myosin Ia inactivation in gastric but not endometrial tumors

    International Journal of Cancer, Vol. 132, Núm. 8, pp. 1790-1799