Sara
Labiano Almiñana
Investigadora
Ignacio
Melero
Catedrático de Universidad
Publicaciones en las que colabora con Ignacio Melero (19)
2019
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Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells
Cancer cell, Vol. 36, Núm. 6, pp. 613-629
2018
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CD137 (4-1BB) Costimulation Modifies DNA Methylation in CD8+ T Cell-Relevant Genes
Cancer Immunology Research, Vol. 6, Núm. 1, pp. 69-78
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Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4–1BB)
OncoImmunology, Vol. 7, Núm. 1
2017
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Cellular immunotherapies for cancer
OncoImmunology, Vol. 6, Núm. 5
2016
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Abscopal effects of radiotherapy are enhanced by combined immunostimulatory mAbs and are dependent on CD8 T cells and crosspriming
Cancer Research, Vol. 76, Núm. 20, pp. 5994-6005
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Deciphering CD137 (4-1BB) signaling in T-cell costimulation for translation into successful cancer immunotherapy
European Journal of Immunology, Vol. 46, Núm. 3, pp. 513-522
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Hypoxia-induced soluble CD137 in malignant cells blocks CD137L-costimulation as an immune escape mechanism
OncoImmunology, Vol. 5, Núm. 1
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Successful immunotherapy against a transplantable mouse squamous lung carcinoma with anti-PD-1 and anti-CD137 monoclonal antibodies
Journal of Thoracic Oncology, Vol. 11, Núm. 4, pp. 524-536
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Tumor-Produced Interleukin-8 Attracts human myeloid-derived suppressor cells and elicits extrusion of Neutrophil Extracellular Traps (NETs)
Clinical Cancer Research, Vol. 22, Núm. 15, pp. 3924-3936
2015
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Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb
Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Núm. 24, pp. 7551-7556
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Functional expression of CD137 (4-1BB) on T helper follicular cells
OncoImmunology, Vol. 4, Núm. 12
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Immune response regulation in the tumor microenvironment by hypoxia
Seminars in Oncology, Vol. 42, Núm. 3, pp. 378-386
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Nivolumab and urelumab enhance antitumor activity of human T lymphocytes engrafted in Rag2-/-IL2Rγnull immunodeficient mice
Cancer Research, Vol. 75, Núm. 17, pp. 3466-3478
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PD-L1/PD-1 presence in the tumor microenvironment and activity of PD-1 blockade in multiple myeloma
Leukemia
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Virotherapy with a Semliki forest virus-based vector encoding IL12 synergizes with PD-1/PD-L1 blockade
Cancer Immunology Research, Vol. 3, Núm. 5, pp. 449-454
2014
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Combinations of immunostimulatory antibodies with synergistic effects against spontaneous cancer
OncoImmunology, Vol. 3, Núm. 1
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Orchestrating immune check-point blockade for cancer immunotherapy in combinations
Current Opinion in Immunology, Vol. 27, Núm. 1, pp. 89-97
2013
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Better performance of CARs deprived of the PD-1 brake
Clinical Cancer Research, Vol. 19, Núm. 20, pp. 5546-5548
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Combined immunostimulatory monoclonal antibodies extend survival in an aggressive transgenic hepatocellular carcinoma mouse model
Clinical Cancer Research, Vol. 19, Núm. 22, pp. 6151-6162