Diana Isabel
Llopiz Khatchikian
Investigadora Asociada
Juan José
Lasarte Sagastibelza
Catedrático de Universidad
Publicaciones en las que colabora con Juan José Lasarte Sagastibelza (24)
2023
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Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
Nature Medicine, Vol. 29, Núm. 3, pp. 632-645
2022
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Gemcitabine-mediated depletion of immunosuppressive dendritic cells enhances the efficacy of therapeutic vaccination
Frontiers in Immunology, Vol. 13
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Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer
Frontiers in Immunology, Vol. 13
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Overcoming T cell dysfunction in acidic pH to enhance adoptive T cell transfer immunotherapy
OncoImmunology, Vol. 11, Núm. 1
2021
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Inhibition of adjuvant-induced TAM receptors potentiates cancer vaccine immunogenicity and therapeutic efficacy
Cancer Letters, Vol. 499, pp. 279-289
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Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses
Emerging Microbes and Infections, Vol. 10, Núm. 1, pp. 1931-1946
2020
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Cold‐inducible rna binding protein as a vaccination platform to enhance immunotherapeutic responses against hepatocellular carcinoma
Cancers, Vol. 12, Núm. 11, pp. 1-18
2019
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Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model
Cancer Immunology, Immunotherapy, Vol. 68, Núm. 3, pp. 379-393
2018
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The Toll like receptor 4 ligand cold-inducible RNA-binding protein as vaccination platform against cancer
OncoImmunology, Vol. 7, Núm. 4
2017
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Blockage of FOXP3 transcription factor dimerization and FOXP3/AML1 interaction inhibits T regulatory cell activity: sequence optimization of a peptide inhibitor
Oncotarget, Vol. 8, Núm. 42, pp. 71709-71724
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IL-10 expression defines an immunosuppressive dendritic cell population induced by antitumor therapeutic vaccination
Oncotarget, Vol. 8, Núm. 2, pp. 2659-2671
2016
2015
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Clinical testing of a dendritic cell targeted therapeutic vaccine in patients with chronic hepatitis C virus infection
Molecular Therapy - Methods and Clinical Development, Vol. 2, pp. 15006
2013
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Helper cell-independent antitumor activity of potent CD8+ T cell epitope peptide vaccines is dependent upon CD40L
OncoImmunology, Vol. 2, Núm. 12, pp. 1-11
2011
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Adjuvant combination and antigen targeting as a strategy to induce polyfunctional and high-avidity T-cell responses against poorly immunogenic tumors
Cancer Research, Vol. 71, Núm. 9, pp. 3214-3224
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Improved dendritic cell-based immunization against hepatitis C virus using peptide inhibitors of interleukin 10
Hepatology, Vol. 53, Núm. 1, pp. 23-31
2010
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A peptide inhibitor of FOXP3 impairs regulatory T cell activity and improves vaccine efficacy in mice
Journal of Immunology, Vol. 185, Núm. 9, pp. 5150-5159
2009
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Peptide inhibitors of transforming growth factor-β enhance the efficacy of antitumor immunotherapy
International Journal of Cancer, Vol. 125, Núm. 11, pp. 2614-2623
2008
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Combined immunization with adjuvant molecules poly(I:C) and anti-CD40 plus a tumor antigen has potent prophylactic and therapeutic antitumor effects
Cancer Immunology, Immunotherapy, Vol. 57, Núm. 1, pp. 19-29
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In vitro and in vivo down-regulation of regulatory T cell activity with a peptide inhibitor of TGF-β1
Journal of Immunology, Vol. 181, Núm. 1, pp. 126-135