Maite
García Fernández de Barrena
Profesional Investigadora
Bruno Carlos
Sangro Gómez-Acebo
Catedrático de Universidad
Publicacións nas que colabora con Bruno Carlos Sangro Gómez-Acebo (17)
2024
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Caspases compromise SLU7 and UPF1 stability and NMD activity during hepatocarcinogenesis
JHEP Reports, Vol. 6, Núm. 8
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Comprehensive in silico CpG methylation analysis in hepatocellular carcinoma identifies tissue- and tumor-type specific marks disconnected from gene expression
Journal of Physiology and Biochemistry
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Identification of PRMT5 as a therapeutic target in cholangiocarcinoma
Gut
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New insights into the regulation of bile acids synthesis during the early stages of liver regeneration: A human and experimental study
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1870, Núm. 5
2023
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Comprehensive analysis of epigenetic and epitranscriptomic genes’ expression in human NAFLD
Journal of Physiology and Biochemistry, Vol. 79, Núm. 4, pp. 901-924
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Identification and experimental validation of druggable epigenetic targets in hepatoblastoma
Journal of Hepatology, Vol. 79, Núm. 4, pp. 989-1005
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Mapping early serum proteome signatures of liver regeneration in living donor liver transplant cases
BioFactors, Vol. 49, Núm. 4, pp. 912-927
2022
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DNA Methylation Regulates a Set of Long Non-Coding RNAs Compromising Hepatic Identity during Hepatocarcinogenesis
Cancers, Vol. 14, Núm. 9
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New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming
Journal of Experimental and Clinical Cancer Research, Vol. 41, Núm. 1
2021
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Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma
Hepatology, Vol. 73, Núm. 6, pp. 2380-2396
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Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: Dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis
Gut, Vol. 70, Núm. 2, pp. 388-400
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Splicing Factor SLU7 Prevents Oxidative Stress-Mediated Hepatocyte Nuclear Factor 4α Degradation, Preserving Hepatic Differentiation and Protecting From Liver Damage
Hepatology, Vol. 74, Núm. 5, pp. 2791-2807
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The splicing regulator SLU7 is required to preserve DNMT1 protein stability and DNA methylation
Nucleic Acids Research, Vol. 49, Núm. 15, pp. 8592-8609
2020
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Dual pharmacological targeting of hdacs and pde5 inhibits liver disease progression in a mouse model of biliary inflammation and fibrosis
Cancers, Vol. 12, Núm. 12, pp. 1-27
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Pilot multi-omic analysis of human bile from benign and malignant biliary strictures: A machine-learning approach
Cancers, Vol. 12, Núm. 6, pp. 1-30
2019
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Splicing events in the control of genome integrity: Role of SLU7 and truncated SRSF3 proteins
Nucleic Acids Research, Vol. 47, Núm. 7, pp. 3450-3466
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The Epidermal Growth Factor Receptor Ligand Amphiregulin Protects From Cholestatic Liver Injury and Regulates Bile Acids Synthesis
Hepatology, Vol. 69, Núm. 4, pp. 1632-1647