Pedro
Berraondo López
Profesional Investigador
Irene
Olivera Valle
Investigadora
Publikationen, an denen er mitarbeitet Irene Olivera Valle (19)
2023
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CD137 (4-1BB) requires physically associated cIAPs for signal transduction and antitumor effects
Science advances, Vol. 9, Núm. 33, pp. eadf6692
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Facts and Hopes on Neutralization of Protumor Inflammatory Mediators in Cancer Immunotherapy
Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 29, Núm. 23, pp. 4711-4727
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Interleukin-18 in cancer immunology and immunotherapy
Expert Opinion on Therapeutic Targets, Vol. 27, Núm. 11, pp. 1035-1042
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Intracavitary adoptive transfer of IL-12 mRNA-engineered tumor-specific CD8+ T cells eradicates peritoneal metastases in mouse models
Oncoimmunology, Vol. 12, Núm. 1, pp. 2147317
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Intraperitoneal administration of a modified vaccinia virus Ankara confers single-chain interleukin-12 expression to the omentum and achieves immune-mediated efficacy against peritoneal carcinomatosis
Journal for immunotherapy of cancer, Vol. 11, Núm. 11
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Intratumoral Gene Transfer of mRNAs Encoding IL12 in Combination with Decoy-Resistant IL18 Improves Local and Systemic Antitumor Immunity
Cancer immunology research, Vol. 11, Núm. 2, pp. 184-198
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Intratumoral immunotherapy with mRNAs encoding chimeric protein constructs encompassing IL-12, CD137 agonists, and TGF-β antagonists
Molecular Therapy - Nucleic Acids, Vol. 33, pp. 668-682
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Intratumoral neoadjuvant immunotherapy based on the BO-112 viral RNA mimetic
OncoImmunology, Vol. 12, Núm. 1
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Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma
Cell Reports Medicine, Vol. 4, Núm. 4
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mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy
Cell Reports Medicine, Vol. 4, Núm. 3
2022
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A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα and IL-1β
Cancer Discovery, Vol. 12, Núm. 9, pp. 2140-2157
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Advances in mRNA-based drug discovery in cancer immunotherapy
Expert Opinion on Drug Discovery, Vol. 17, Núm. 1, pp. 41-53
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Depletion of Conventional Type-1 Dendritic Cells in Established Tumors Suppresses Immunotherapy Efficacy
Cancer research, Vol. 82, Núm. 23, pp. 4373-4385
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Novel strategies exploiting interleukin-12 in cancer immunotherapy
Pharmacology and Therapeutics, Vol. 239
2021
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Differential Interleukin-8 thresholds for chemotaxis and netosis in human neutrophils
European Journal of Immunology, Vol. 51, Núm. 9, pp. 2274-2280
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IL8, neutrophils, and NETs in a collusion against cancer immunity and immunotherapy
Clinical Cancer Research, Vol. 27, Núm. 9, pp. 2383-2393
2020
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Engineering bionic T cells: signal 1, signal 2, signal 3, reprogramming and the removal of inhibitory mechanisms
Cellular and Molecular Immunology, Vol. 17, Núm. 6, pp. 576-586
2019
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Immune desertic landscapes in hepatocellular carcinoma shaped by β-catenin activation
Cancer Discovery, Vol. 9, Núm. 8, pp. 1003-1005
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Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells
Cancer cell, Vol. 36, Núm. 6, pp. 613-629