Cristian
Smerdou Picazo
Profesional Investigador
Centro de Investigación Médica Aplicada
Pamplona, EspañaPublications in collaboration with researchers from Centro de Investigación Médica Aplicada (50)
2024
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DNA electroporation in a vacuum: A “shocking” innovation for vaccines
Molecular Therapy Nucleic Acids
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Oleuropein-driven reprogramming of the myeloid cell compartment to sensitise tumours to PD-1/PD-L1 blockade strategies
British Journal of Cancer, Vol. 130, Núm. 5, pp. 869-879
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Self-Amplifying RNA: A Second Revolution of mRNA Vaccines against COVID-19
Vaccines, Vol. 12, Núm. 3
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Targeting IL-6 trans-signalling by sgp130Fc attenuates severity in SARS-CoV-2 -infected mice and reduces endotheliopathy
eBioMedicine, Vol. 103
2023
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AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity
Biomedicine and Pharmacotherapy, Vol. 169
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Checkpoint blockade meets gene therapy: Opportunities to improve response and reduce toxicity
International Review of Cell and Molecular Biology (Elsevier Inc.), pp. 43-86
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JNK Activation in Alzheimer’s Disease Is Driven by Amyloid β and Is Associated with Tau Pathology
ACS Chemical Neuroscience
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JNK3 Overexpression in the Entorhinal Cortex Impacts on the Hippocampus and Induces Cognitive Deficiencies and Tau Misfolding
ACS Chemical Neuroscience, Vol. 14, Núm. 11, pp. 2074-2088
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Local Delivery of Immunomodulatory Antibodies for Gastrointestinal Tumors
Cancers, Vol. 15, Núm. 8
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Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses
Cancer Letters, Vol. 561
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Photodynamic nasal SARS-CoV-2 decolonization shortens infectivity and influences specific T-Cell responses
Frontiers in Cellular and Infection Microbiology, Vol. 13
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Treatment with the senolytics dasatinib/quercetin reduces SARS-CoV-2-related mortality in mice
Aging Cell, Vol. 22, Núm. 3
2022
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A minimal bile salt excretory pump promoter allows bile acid-driven physiological regulation of transgene expression from a gene therapy vector
Cell and Bioscience, Vol. 12, Núm. 1
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Galectin-3 inhibition boosts the therapeutic efficacy of Semliki Forest virus in pediatric osteosarcoma
Molecular Therapy - Oncolytics, Vol. 26, pp. 246-264
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Gene Therapy for Acquired and Genetic Cholestasis
Biomedicines, Vol. 10, Núm. 6
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Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer
Frontiers in Immunology, Vol. 13
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Intratumoral electroporation of a self-amplifying RNA expressing IL-12 induces antitumor effects in mouse models of cancer
Molecular Therapy - Nucleic Acids, Vol. 29, pp. 387-399
2021
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A proteomic atlas of lineage and cancer-polarized expression modules in myeloid cells modeling immunosuppressive tumor-infiltrating subsets
Journal of Personalized Medicine, Vol. 11, Núm. 6
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Adenovirus-mediated inducible expression of a pd-l1 blocking antibody in combination with macrophage depletion improves survival in a mouse model of peritoneal carcinomatosis
International Journal of Molecular Sciences, Vol. 22, Núm. 8
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Astrocytic GLUT1 ablation improves systemic glucose metabolism and promotes cognition
Alzheimer's & dementia : the journal of the Alzheimer's Association, Vol. 17, pp. e058650