Publications by the researcher in collaboration with Julen Oyarzabal Santamarina (6)

2022

  1. CM-352 Efficacy in a Mouse Model of Anticoagulant-Associated Intracranial Hemorrhage

    Thrombosis and Haemostasis, Vol. 122, Núm. 8, pp. 1314-1325

2019

  1. Trimethylamine-N-Oxide (TMAO) Predicts Cardiovascular Mortality in Peripheral Artery Disease

    Scientific Reports, Vol. 9, Núm. 1

2018

  1. Phenotypic Screening to Discover Novel Chemical Series as Efficient Antihemorrhagic Agents

    ACS Medicinal Chemistry Letters, Vol. 9, Núm. 5, pp. 428-433

2017

  1. CM352 reduces brain damage and improves functional recovery in a rat model of intracerebral hemorrhage

    Journal of the American Heart Association, Vol. 6, Núm. 6

2015

  1. Design, synthesis, and biological evaluation of novel matrix metalloproteinase inhibitors as potent antihemorrhagic agents: From hit identification to an optimized lead

    Journal of Medicinal Chemistry, Vol. 58, Núm. 5, pp. 2465-2488

  2. Discovery and Safety Profiling of a Potent Preclinical Candidate, (4-[4-[[(3 R)-3-(Hydroxycarbamoyl)-8-azaspiro[4.5]decan-3-yl]sulfonyl]phenoxy]- N -methylbenzamide) (CM-352), for the Prevention and Treatment of Hemorrhage

    Journal of Medicinal Chemistry, Vol. 58, Núm. 7, pp. 2941-2957