(FM) Medicina Interna
Departamento académico
Carlos
Alfaro Alegría
Investigador hasta 2017
Publicaciones en las que colabora con Carlos Alfaro Alegría (30)
2014
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Serum interleukin-8 reflects tumor burden and treatment response across malignancies of multiple tissue origins
Clinical Cancer Research, Vol. 20, Núm. 22, pp. 5697-5707
2013
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A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C
Journal of Hepatology, Vol. 59, Núm. 1, pp. 81-88
2012
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CD8 T cell priming in the presence of IFN-α renders CTLs with improved responsiveness to homeostatic cytokines and recall antigens: important traits for adoptive T cell therapy
Journal of Immunology, Vol. 189, Núm. 7, pp. 3299-3310
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Liver Gene Transfer of Interkeukin-15 Constructs That Become Part of Circulating High Density Lipoproteins for Immunotherapy
PLoS ONE, Vol. 7, Núm. 12
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The HIF-1α hypoxia response in tumor-infi ltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy
Cancer Discovery, Vol. 2, Núm. 7, pp. 608-623
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Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates.
Journal of translational medicine, Vol. 10, pp. 122
2011
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Carcinoma-derived Interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation
PLoS ONE, Vol. 6, Núm. 3
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Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes
PLoS ONE, Vol. 6, Núm. 12
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Intratumoral injection of interferon-α and systemic delivery of agonist anti-CD137 monoclonal antibodies synergize for immunotherapy
International Journal of Cancer, Vol. 128, Núm. 1, pp. 105-118
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Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients
Journal of Immunology, Vol. 187, Núm. 11, pp. 6130-6142
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Synergistic effects of CTLA-4 blockade with tremelimumab and elimination of regulatory T lymphocytes in vitro and in vivo
International Journal of Cancer, Vol. 129, Núm. 2, pp. 374-386
2010
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Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-α
European Journal of Immunology, Vol. 40, Núm. 11, pp. 3054-3063
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Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates
Molecular Therapy, Vol. 18, Núm. 4, pp. 754-765
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Interferon producing killer dendritic cells (IKDC): A matter of controversy
Inmunologia, Vol. 29, Núm. 1, pp. 50-55
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Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 8, pp. 1223-1233
2009
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Clinical development of combination strategies in immunotherapy: Are we ready for more than one investigational product in an early clinical trial?
Immunotherapy, Vol. 1, Núm. 5, pp. 845-853
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In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb
European Journal of Immunology, Vol. 39, Núm. 9, pp. 2424-2436
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Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes
British Journal of Cancer, Vol. 100, Núm. 7, pp. 1111-1119
2008
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Interleukin-15 liver gene transfer increases the number and function of IKDCs and NK cells
Gene Therapy, Vol. 15, Núm. 7, pp. 473-483
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Therapeutic antitumor efficacy of anti-CD137 agonistic monoclonal antibody in mouse models of myeloma
Clinical Cancer Research, Vol. 14, Núm. 21, pp. 6895-6906