(FM) Medicina Interna
Departamento académico
José Luis
Pérez Gracia
Consultor Médico
Publicaciones en las que colabora con José Luis Pérez Gracia (31)
2024
2020
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Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade
Nature cancer, Vol. 1, Núm. 1, pp. 75-85
2018
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Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced lung cancer
Cancer Medicine, Vol. 7, Núm. 7, pp. 3474-3483
2014
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Serum interleukin-8 reflects tumor burden and treatment response across malignancies of multiple tissue origins
Clinical Cancer Research, Vol. 20, Núm. 22, pp. 5697-5707
2013
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A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C
Journal of Hepatology, Vol. 59, Núm. 1, pp. 81-88
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Investigation of complement activation product C4d as a diagnostic and prognostic biomarker for lung cancer
Journal of the National Cancer Institute, Vol. 105, Núm. 18, pp. 1385-1393
2012
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The HIF-1α hypoxia response in tumor-infi ltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy
Cancer Discovery, Vol. 2, Núm. 7, pp. 608-623
2011
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Agonist anti-CD137 mAb act on tumor endothelial cells to enhance recruitment of activated T lymphocytes
Cancer Research, Vol. 71, Núm. 3, pp. 801-811
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Assessment of epidermal growth factor receptor and krasmutation status in cytological stained smears of non-small celllung cancer patients: Correlation with clinical outcomes
Oncologist, Vol. 16, Núm. 6, pp. 877-885
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Carcinoma-derived Interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation
PLoS ONE, Vol. 6, Núm. 3
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Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes
PLoS ONE, Vol. 6, Núm. 12
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Direct effects of type I interferons on cells of the immune system
Clinical Cancer Research, Vol. 17, Núm. 9, pp. 2619-2627
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Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients
Journal of Immunology, Vol. 187, Núm. 11, pp. 6130-6142
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Synergistic effects of CTLA-4 blockade with tremelimumab and elimination of regulatory T lymphocytes in vitro and in vivo
International Journal of Cancer, Vol. 129, Núm. 2, pp. 374-386
2010
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Delivery of immunostimulatory monoclonal antibodies by encapsulated hybridoma cells
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 11, pp. 1621-1631
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Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 8, pp. 1223-1233
2009
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Clinical development of combination strategies in immunotherapy: Are we ready for more than one investigational product in an early clinical trial?
Immunotherapy, Vol. 1, Núm. 5, pp. 845-853
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In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb
European Journal of Immunology, Vol. 39, Núm. 9, pp. 2424-2436
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Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes
British Journal of Cancer, Vol. 100, Núm. 7, pp. 1111-1119