(FM) Medicina Interna
Departamento académico
Julen
Oyarzabal Santamarina
Ikertzailea 2018-(e)ra arte
Julen Oyarzabal Santamarina-rekin lankidetzan egindako argitalpenak (18)
2024
2021
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Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma
Hepatology, Vol. 73, Núm. 6, pp. 2380-2396
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Endogenous retroelement activation by epigenetic therapy reverses the warburg effect and elicits mitochondrial-mediated cancer cell death
Cancer Discovery, Vol. 11, Núm. 5, pp. 1268-1285
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Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: Dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis
Gut, Vol. 70, Núm. 2, pp. 388-400
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Searching for peptide inhibitors of t regulatory cell activity by targeting specific domains of foxp3 transcription factor
Biomedicines, Vol. 9, Núm. 2, pp. 1-20
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mRNA-based therapy in a rabbit model of variegate porphyria offers new insights into the pathogenesis of acute attacks
Molecular Therapy - Nucleic Acids, Vol. 25, pp. 207-219
2020
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Dual pharmacological targeting of hdacs and pde5 inhibits liver disease progression in a mouse model of biliary inflammation and fibrosis
Cancers, Vol. 12, Núm. 12, pp. 1-27
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Re: Inhibition of a G9a/DNMT Network Triggers Immune-Mediated Bladder Cancer Regression
Journal of Urology
2019
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Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma
Hepatology, Vol. 69, Núm. 2, pp. 587-603
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Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression
Nature Medicine
2018
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Targeting the anion exchanger 2 with specific peptides as a new therapeutic approach in b lymphoid neoplasms
Haematologica, Vol. 103, Núm. 6, pp. 1065-1072
2017
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Blockage of FOXP3 transcription factor dimerization and FOXP3/AML1 interaction inhibits T regulatory cell activity: sequence optimization of a peptide inhibitor
Oncotarget, Vol. 8, Núm. 42, pp. 71709-71724
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Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies
Nature Communications, Vol. 8
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Identification of LAG3 high affinity aptamers by HT-SELEX and Conserved Motif Accumulation (CMA)
PLoS ONE, Vol. 12, Núm. 9
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Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome
PLoS ONE, Vol. 12, Núm. 12
2016
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In Silico Aptamer Docking Studies: From a Retrospective Validation to a Prospective Case Study'TIM3 Aptamers Binding
Molecular Therapy - Nucleic Acids, Vol. 5, pp. e376
2015
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Inhibition of FOXP3/NFAT interaction enhances T cell function after TCR stimulation
Journal of Immunology, Vol. 195, Núm. 7, pp. 3180-3189