(FM) Medicina Interna
Departamento académico
Xabier
Aguirre Ena
Profesional Investigador
Xabier Aguirre Ena-rekin lankidetzan egindako argitalpenak (18)
2024
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Rna-loaded nanoparticles for the treatment of hematological cancers
Advanced Drug Delivery Reviews, Vol. 214
2023
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Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
Nature Medicine, Vol. 29, Núm. 3, pp. 632-645
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Revealing cell populations catching the early stages of human embryo development in naive pluripotent stem cell cultures
Stem Cell Reports, Vol. 18, Núm. 1, pp. 64-80
2022
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Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma
Frontiers in Immunology, Vol. 13
2021
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Endogenous retroelement activation by epigenetic therapy reverses the warburg effect and elicits mitochondrial-mediated cancer cell death
Cancer Discovery, Vol. 11, Núm. 5, pp. 1268-1285
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Epigenetic Modifiers: Anti-Neoplastic Drugs With Immunomodulating Potential
Frontiers in Immunology, Vol. 12
2020
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Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma
Genome Research, Vol. 30, Núm. 9, pp. 1217-1227
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Re: Inhibition of a G9a/DNMT Network Triggers Immune-Mediated Bladder Cancer Regression
Journal of Urology
2019
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Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma
Hepatology, Vol. 69, Núm. 2, pp. 587-603
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Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression
Nature Medicine
2018
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Deregulation of linc-PINT in acute lymphoblastic leukemia is implicated in abnormal proliferation of leukemic cells
Oncotarget, Vol. 9, Núm. 16, pp. 12842-12852
2017
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Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies
Nature Communications, Vol. 8
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Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome
PLoS ONE, Vol. 12, Núm. 12
2015
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Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers
Genome Research, Vol. 25, Núm. 4, pp. 478-487
2013
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Long non-coding RNAs in haematological malignancies
International Journal of Molecular Sciences, Vol. 14, Núm. 8, pp. 15386-15422
2009
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Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia
Cancer Research, Vol. 69, Núm. 10, pp. 4443-4453
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microRNA-451 regulates macrophage migration inhibitory factor production and proliferation of gastrointestinal cancer cells
Clinical Cancer Research, Vol. 15, Núm. 7, pp. 2281-2290
2008
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Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth
Molecular Cancer Research, Vol. 6, Núm. 12, pp. 1830-1840