(FM) Medicina Interna
Departamento académico
Iker
Uriarte Díaz-Varela
Investigador
Publicaciones en las que colabora con Iker Uriarte Díaz-Varela (38)
2024
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Identification of PRMT5 as a therapeutic target in cholangiocarcinoma
Gut
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New insights into the regulation of bile acids synthesis during the early stages of liver regeneration: A human and experimental study
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1870, Núm. 5
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Non-mitogenic FGF19 mRNA-based therapy for the treatment of experimental metabolic dysfunction-associated steatotic liver disease (MASLD)
Clinical science (London, England : 1979), Vol. 138, Núm. 20, pp. 1265-1284
2023
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A new FGF15/19-mediated gut-to-heart axis controls cardiac hypertrophy
Journal of Pathology, Vol. 261, Núm. 3, pp. 335-348
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Comprehensive analysis of epigenetic and epitranscriptomic genes’ expression in human NAFLD
Journal of Physiology and Biochemistry, Vol. 79, Núm. 4, pp. 901-924
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Identification and experimental validation of druggable epigenetic targets in hepatoblastoma
Journal of Hepatology, Vol. 79, Núm. 4, pp. 989-1005
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Mapping early serum proteome signatures of liver regeneration in living donor liver transplant cases
BioFactors, Vol. 49, Núm. 4, pp. 912-927
2022
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New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming
Journal of Experimental and Clinical Cancer Research, Vol. 41, Núm. 1
2021
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Armcx3 mediates susceptibility to hepatic tumorigenesis promoted by dietary lipotoxicity
Cancers, Vol. 13, Núm. 5, pp. 1-22
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Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma
Hepatology, Vol. 73, Núm. 6, pp. 2380-2396
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Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: Dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis
Gut, Vol. 70, Núm. 2, pp. 388-400
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FGF15/19 is required for adipose tissue plasticity in response to thermogenic adaptations
Molecular Metabolism, Vol. 43
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Gene supplementation of CYP27A1 in the liver restores bile acid metabolism in a mouse model of cerebrotendinous xanthomatosis
Molecular Therapy - Methods and Clinical Development, Vol. 22, pp. 210-221
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Splicing Factor SLU7 Prevents Oxidative Stress-Mediated Hepatocyte Nuclear Factor 4α Degradation, Preserving Hepatic Differentiation and Protecting From Liver Damage
Hepatology, Vol. 74, Núm. 5, pp. 2791-2807
2020
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Dual pharmacological targeting of hdacs and pde5 inhibits liver disease progression in a mouse model of biliary inflammation and fibrosis
Cancers, Vol. 12, Núm. 12, pp. 1-27
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Pilot multi-omic analysis of human bile from benign and malignant biliary strictures: A machine-learning approach
Cancers, Vol. 12, Núm. 6, pp. 1-30
2019
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Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma
Hepatology, Vol. 69, Núm. 2, pp. 587-603
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Liver Expression of a MiniATP7B Gene Results in Long-Term Restoration of Copper Homeostasis in a Wilson Disease Model in Mice
Hepatology, Vol. 70, Núm. 1, pp. 108-126
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Splicing events in the control of genome integrity: Role of SLU7 and truncated SRSF3 proteins
Nucleic Acids Research, Vol. 47, Núm. 7, pp. 3450-3466
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The Epidermal Growth Factor Receptor Ligand Amphiregulin Protects From Cholestatic Liver Injury and Regulates Bile Acids Synthesis
Hepatology, Vol. 69, Núm. 4, pp. 1632-1647