(FM) Medicina Interna
Departamento académico
Diego Oscar
Alignani
Profesional Investigador
Publicaciones en las que colabora con Diego Oscar Alignani (14)
2022
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CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome
Science Advances, Vol. 8, Núm. 39
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Gemcitabine-mediated depletion of immunosuppressive dendritic cells enhances the efficacy of therapeutic vaccination
Frontiers in Immunology, Vol. 13
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TCR-induced FOXP3 expression by CD8+ T cells impairs their anti-tumor activity
Cancer Letters, Vol. 528, pp. 45-58
2021
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Immunologic characterization of COVID-19 patients with hematological cancer
Haematologica
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Immunological Biomarkers of Fatal COVID-19: A Study of 868 Patients
Frontiers in Immunology, Vol. 12
2020
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Id1 and pd-1 combined blockade impairs tumor growth and survival of KRAS-mutant lung cancer by stimulating PD-l1 expression and tumor infiltrating CD8+ T cells
Cancers, Vol. 12, Núm. 11, pp. 1-22
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Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade
Nature cancer, Vol. 1, Núm. 1, pp. 75-85
2019
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PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas
Blood, Vol. 133, Núm. 22, pp. 2401-2412
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Splicing events in the control of genome integrity: Role of SLU7 and truncated SRSF3 proteins
Nucleic Acids Research, Vol. 47, Núm. 7, pp. 3450-3466
2017
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Expansion of tumor-infiltrating CD8+ T cells expressing PD-1 improves the efficacy of adoptive T-cell therapy
Cancer Research, Vol. 77, Núm. 13, pp. 3672-3684
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IL-10 expression defines an immunosuppressive dendritic cell population induced by antitumor therapeutic vaccination
Oncotarget, Vol. 8, Núm. 2, pp. 2659-2671
2015
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Chronic exposure to IFNα drives medullar lymphopoiesis towards t-cell differentiation in mice
Haematologica, Vol. 100, Núm. 8, pp. 1014-1022
2014
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Conventional but not plasmacytoid dendritic cells foster the systemic virus-induced type I IFN response needed for efficient CD8 T cell priming
Journal of Immunology, Vol. 193, Núm. 3, pp. 1151-1161
2012
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CD8 T cell priming in the presence of IFN-α renders CTLs with improved responsiveness to homeostatic cytokines and recall antigens: important traits for adoptive T cell therapy
Journal of Immunology, Vol. 189, Núm. 7, pp. 3299-3310