(FM) Oncología
Departamento académico
Sandra
Hervas Stubbs
Profesional Investigadora
Publicaciones en las que colabora con Sandra Hervas Stubbs (31)
2023
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mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy
Cell Reports Medicine, Vol. 4, Núm. 3
2022
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Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer
Frontiers in Immunology, Vol. 13
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Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
Cancer Discovery, Vol. 12, Núm. 5, pp. 1356-1377
2021
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The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes
British Journal of Cancer, Vol. 124, Núm. 6, pp. 1138-1149
2019
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Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells
Cancer cell, Vol. 36, Núm. 6, pp. 613-629
2015
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Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12
Cancer Research, Vol. 75, Núm. 3, pp. 497-507
2013
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Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein
Cancer Research, Vol. 73, Núm. 1, pp. 139-149
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Combined immunostimulatory monoclonal antibodies extend survival in an aggressive transgenic hepatocellular carcinoma mouse model
Clinical Cancer Research, Vol. 19, Núm. 22, pp. 6151-6162
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Interleukin-15 in gene therapy of cancer
Current Gene Therapy, Vol. 13, Núm. 1, pp. 15-30
2012
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CD8 T cell priming in the presence of IFN-α renders CTLs with improved responsiveness to homeostatic cytokines and recall antigens: important traits for adoptive T cell therapy
Journal of Immunology, Vol. 189, Núm. 7, pp. 3299-3310
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Immunotherapeutic synergy between anti-CD137 mAb and intratumoral administration of a cytopathic semliki forest virus encoding IL-12
Molecular Therapy, Vol. 20, Núm. 9, pp. 1664-1675
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The HIF-1α hypoxia response in tumor-infi ltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy
Cancer Discovery, Vol. 2, Núm. 7, pp. 608-623
2011
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Agonist anti-CD137 mAb act on tumor endothelial cells to enhance recruitment of activated T lymphocytes
Cancer Research, Vol. 71, Núm. 3, pp. 801-811
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Carcinoma-derived Interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation
PLoS ONE, Vol. 6, Núm. 3
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Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes
PLoS ONE, Vol. 6, Núm. 12
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Direct effects of type I interferons on cells of the immune system
Clinical Cancer Research, Vol. 17, Núm. 9, pp. 2619-2627
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Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients
Journal of Immunology, Vol. 187, Núm. 11, pp. 6130-6142
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Synergistic effects of CTLA-4 blockade with tremelimumab and elimination of regulatory T lymphocytes in vitro and in vivo
International Journal of Cancer, Vol. 129, Núm. 2, pp. 374-386
2010
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Delivery of immunostimulatory monoclonal antibodies by encapsulated hybridoma cells
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 11, pp. 1621-1631
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Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 8, pp. 1223-1233