Centro de Investigación de Medicina Aplicada (CIMA)
Centro / Instituto vinculado a la Universidad de Navarra
Juan Carlos
Ruiz Ruiz
Publicaciones en las que colabora con Juan Carlos Ruiz Ruiz (22)
2016
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Phase I open label liver-directed gene therapy clinical trial for acute intermittent porphyria
Journal of Hepatology, Vol. 65, Núm. 4, pp. 776-783
2011
2010
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Effects of IFN-α as a signal-3 cytokine on human naïve and antigen-experienced CD8+ T cells
European Journal of Immunology, Vol. 40, Núm. 12, pp. 3389-3402
2009
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Production of recombinant woodchuck IFNα and development of monoclonal antibodies
Journal of Interferon and Cytokine Research, Vol. 29, Núm. 2, pp. 75-81
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Treatment of chronic viral hepatitis in woodchucks by prolonged intrahepatic expression of interleukin-12
Journal of Virology, Vol. 83, Núm. 6, pp. 2663-2674
2007
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Woodchuck dendritic cells generated from peripheral blood mononuclear cells and transduced with recombinant human adenovirus serotype 5 induce antigen-specific cellular immune responses
Journal of Medical Virology, Vol. 79, Núm. 5, pp. 522-529
2005
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Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8
International Journal of Cancer, Vol. 116, Núm. 2, pp. 275-281
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Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus
Vaccine, Vol. 23, Núm. 27, pp. 3493-3499
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IFN-α gene therapy for woodchuck hepatitis with adeno-associated virus: Differences in duration of gene expression and antiviral activity using intraportal or intramuscular routes
Molecular Therapy, Vol. 12, Núm. 1, pp. 68-76
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Induction of gp120-specific protective immune responses by genetic vaccination with linear polyethylenimine-plasmid complex
Vaccine, Vol. 23, Núm. 11, pp. 1384-1392
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Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas
Journal of Clinical Oncology, Vol. 23, Núm. 5, pp. 999-1010
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Modulation of vaccine-induced immune responses to hepatitis C virus in rhesus macaques by altering priming before adenovirus boosting
Journal of Infectious Diseases, Vol. 192, Núm. 5, pp. 920-929
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Topical application of a peptide inhibitor of transforming growth factor-β1 ameliorates bleomycin-induced skin fibrosis
Journal of Investigative Dermatology, Vol. 125, Núm. 3, pp. 450-455
2004
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Phase I trial of intratumoral injection of an adenovirus encoding interleukin-12 for advanced digestive tumors
Journal of Clinical Oncology, Vol. 22, Núm. 8, pp. 1389-1397
2002
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Gene therapy for liver diseases: Recent strategies for treatment of viral hepatitis and liver malignancies
Gut, Vol. 50, Núm. 1, pp. 130-135
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The woodchuck interferon-α system: Cloning, family description, and biologic activity
Journal of Medical Virology, Vol. 68, Núm. 3, pp. 424-432
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Vaccination with an adenoviral vector encoding hepatitis C virus (HCV) NS3 protein protects against infection with HCV-recombinant vaccinia virus
Vaccine, Vol. 21, Núm. 3-4, pp. 202-210
2001
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Genetic heterogeneity in the toxicity to systemic adenoviral gene transfer of interleukin-12
Gene Therapy, Vol. 8, Núm. 4, pp. 259-267
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Protection against woodchuck hepatitis virus (WHV) infection by gene gun coimmunization with WHV core and interleukin-12
Journal of Virology, Vol. 75, Núm. 19, pp. 9068-9076
2000
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Pathological and virological findings in patients with persistent hypertransaminasaemia of unknown aetiology
Gut, Vol. 47, Núm. 3, pp. 429-435