Centro de Investigación de Medicina Aplicada (CIMA)
Centro / Instituto vinculado a la Universidad de Navarra
Joaquín
Fernández Irigoyen
Publicaciones en las que colabora con Joaquín Fernández Irigoyen (29)
2024
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Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis
Science Advances , Vol. 10, Núm. 42
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Oleuropein-driven reprogramming of the myeloid cell compartment to sensitise tumours to PD-1/PD-L1 blockade strategies
British Journal of Cancer, Vol. 130, Núm. 5, pp. 869-879
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PD-1/LAG-3 co-signaling profiling uncovers CBL ubiquitin ligases as key immunotherapy targets
EMBO Molecular Medicine, Vol. 16, Núm. 8, pp. 1791-1816
2023
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Improvement of cognitive function in wild-type and Alzheimer´s disease mouse models by the immunomodulatory properties of menthol inhalation or by depletion of T regulatory cells
Frontiers in Immunology, Vol. 14
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Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer
Nature Communications, Vol. 14, Núm. 1
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Stabilization of 14-3-3 protein-protein interactions with Fusicoccin-A decreases alpha-synuclein dependent cell-autonomous death in neuronal and mouse models
Neurobiology of Disease, Vol. 183
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The Regulators of Peroxisomal Acyl-Carnitine Shuttle CROT and CRAT Promote Metastasis in Melanoma
Journal of Investigative Dermatology, Vol. 143, Núm. 2, pp. 305-316.e5
2022
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Circulating Low Density Neutrophils Are Associated with Resistance to First Line Anti-PD1/PDL1 Immunotherapy in Non-Small Cell Lung Cancer
Cancers, Vol. 14, Núm. 16
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NADPH Oxidase 5 (NOX5) Overexpression Promotes Endothelial Dysfunction via Cell Apoptosis, Migration, and Metabolic Alterations in Human Brain Microvascular Endothelial Cells (hCMEC/D3)
Antioxidants, Vol. 11, Núm. 11
2021
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A proteomic atlas of lineage and cancer-polarized expression modules in myeloid cells modeling immunosuppressive tumor-infiltrating subsets
Journal of Personalized Medicine, Vol. 11, Núm. 6
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Amyloid-driven tau accumulation on mitochondria potentially leads to cognitive deterioration in alzheimer’s disease
International Journal of Molecular Sciences, Vol. 22, Núm. 21
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Olfactory Characterization and Training in Older Adults: Protocol Study
Frontiers in Aging Neuroscience, Vol. 13
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Understanding the molecular mechanism of mir-877-3p could provide potential biomarkers and therapeutic targets in squamous cell carcinoma of the cervix
Cancers, Vol. 13, Núm. 7
2020
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N-terminal acetylation mutants affect alpha-synuclein stability, protein levels and neuronal toxicity
Neurobiology of Disease, Vol. 137
2019
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CT-1 (Cardiotrophin-1)-Gal-3 (Galectin-3) axis in cardiac fibrosis and inflammation: Mechanistic insights and clinical implications
Hypertension, Vol. 73, Núm. 3, pp. 602-611
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Oncolytic adenovirus Delta-24-RGD induces a widespread glioma proteotype remodeling during autophagy
Journal of Proteomics, Vol. 194, pp. 168-178
2018
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MicroRNA-506 promotes primary biliary cholangitis–like features in cholangiocytes and immune activation
Hepatology, Vol. 67, Núm. 4, pp. 1420-1440
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Spatial and temporal proteome dynamics of glioma cells during oncolytic adenovirus Delta-24-RGD infection
Oncotarget, Vol. 9, Núm. 57, pp. 31045-31065
2016
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Drafting the proteome landscape of myeloid-derived suppressor cells
Proteomics, Vol. 16, Núm. 2, pp. 367-378
2015
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A core of kinase-regulated interactomes defines the neoplastic MDSC lineage
Oncotarget, Vol. 6, Núm. 29, pp. 27160-27175