Centro de Investigación de Medicina Aplicada (CIMA)
Centro / Instituto vinculado a la Universidad de Navarra
María D.
Odero
Investigadora hasta 2024
Publicaciones en las que colabora con María D. Odero (48)
2023
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Activation of the PP2A-B56α heterocomplex synergizes with venetoclax therapies in AML through BCL2 and MCL1 modulation
Blood, Vol. 141, Núm. 9, pp. 1047-1059
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Regulation and role of the PP2A-B56 holoenzyme family in cancer
Biochimica et Biophysica Acta - Reviews on Cancer, Vol. 1878, Núm. 5
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Set Protein Is Involved in FLT3 Membrane Trafficking
Cancers, Vol. 15, Núm. 8
2021
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Endogenous retroelement activation by epigenetic therapy reverses the warburg effect and elicits mitochondrial-mediated cancer cell death
Cancer Discovery, Vol. 11, Núm. 5, pp. 1268-1285
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Tumor cells in light-chain amyloidosis and myeloma show distinct transcriptional rewiring of normal plasma cell development
Blood, Vol. 138, Núm. 17, pp. 1583-1589
2020
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A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia
Blood Cancer Journal, Vol. 10, Núm. 1
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A novel FTY720 analogue targets SET-PP2A interaction and inhibits growth of acute myeloid leukemia cells without inducing cardiac toxicity
Cancer Letters, Vol. 468, pp. 1-13
2017
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MYC-dependent recruitment of RUNX1 and GATA2 on the SET oncogene promoter enhances PP2A inactivation in acute myeloid leukemia
Oncotarget, Vol. 8, Núm. 33, pp. 53989-54003
2016
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Protein phosphatase 2A as a therapeutic target in acute myeloid leukemia
Frontiers in Oncology, Vol. 6, Núm. APR
2014
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Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels
Journal of Hematology and Oncology, Vol. 7, Núm. 1
2013
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Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription
Oncogene, Vol. 32, Núm. 16, pp. 2069-2078
2012
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Epigenetic regulation of miRNA genes in acute leukemia
Leukemia, Vol. 26, Núm. 3, pp. 395-403
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Mutation patterns of 16 genes in primary and secondary acute myeloid leukemia (AML) with normal cytogenetics
PLoS ONE, Vol. 7, Núm. 8
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Overexpression of GATA2 predicts an adverse prognosis for patients with acute myeloid leukemia and it is associated with distinct molecular abnormalities
Leukemia
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The role of the GATA2 transcription factor in normal and malignant hematopoiesis
Critical Reviews in Oncology/Hematology, Vol. 82, Núm. 1, pp. 1-17
2011
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Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemia
Haematologica, Vol. 96, Núm. 10, pp. 1448-1456
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Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas
PLoS ONE, Vol. 6, Núm. 10
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PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect
Leukemia, Vol. 25, Núm. 4, pp. 606-614
2010
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EVI1 controls proliferation in acute myeloid leukaemia through modulation of miR-1-2
British Journal of Cancer, Vol. 103, Núm. 8, pp. 1292-1296
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SETBP1 overexpression is a novel leukemogenic mechanism that predicts adverse outcome in elderly patients with acute myeloid leukemia
Blood, Vol. 115, Núm. 3, pp. 615-625