(FC) Bioquímica y Genética
Departamento académico
Juan José
Lasarte Sagastibelza
Catedrático de Universidad
Juan José Lasarte Sagastibelza-rekin lankidetzan egindako argitalpenak (21)
2023
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Plasma fractalkine contributes to systemic myeloid diversity and PD-L1/PD-1 blockade in lung cancer
EMBO Reports, Vol. 24, Núm. 8
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Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
Nature Medicine, Vol. 29, Núm. 3, pp. 632-645
2022
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Overcoming T cell dysfunction in acidic pH to enhance adoptive T cell transfer immunotherapy
OncoImmunology, Vol. 11, Núm. 1
2021
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SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation
Journal for ImmunoTherapy of Cancer, Vol. 9, Núm. 3
2020
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Id1 and pd-1 combined blockade impairs tumor growth and survival of KRAS-mutant lung cancer by stimulating PD-l1 expression and tumor infiltrating CD8+ T cells
Cancers, Vol. 12, Núm. 11, pp. 1-22
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Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade
Nature cancer, Vol. 1, Núm. 1, pp. 75-85
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The involvement of ADAM10 in acantholysis in mucocutaneous pemphigus vulgaris depends on the autoantibody profile of each patient
British Journal of Dermatology, Vol. 182, Núm. 5, pp. 1194-1204
2019
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PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas
Blood, Vol. 133, Núm. 22, pp. 2401-2412
2017
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A combined PD-1/C5a blockade synergistically protects against lung cancer growth and metastasis
Cancer Discovery, Vol. 7, Núm. 7, pp. 694-703
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Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies
Nature Communications, Vol. 8
2012
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Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression
Journal of Immunology, Vol. 189, Núm. 9, pp. 4674-4683
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Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses
Vaccine, Vol. 30, Núm. 18, pp. 2848-2858
2005
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Is plasma cardiotrophin-1 a marker of hypertensive heart disease?
Journal of Hypertension, Vol. 23, Núm. 3, pp. 625-632
2003
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Peptide inhibitors of hepatitis C virus NS3 protease
Antiviral Chemistry and Chemotherapy, Vol. 14, Núm. 5, pp. 225-233
2002
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Inhibitory Effect against Polymerase and Ribonuclease Activities of HIV-reverse Transcriptase of the Aqueous Leaf Extract of Terminalia triflora
Phytotherapy Research, Vol. 16, Núm. 8, pp. 778-780
1999
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Argentine plant extracts active against polymerase and ribonuclease H activities of HIV-1 reverse transcriptase
Phytotherapy Research, Vol. 13, Núm. 3, pp. 206-209
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Synthesis and anti-HIV-1 activities of new pyrimido[5,4-b]indoles
Farmaco, Vol. 54, Núm. 4, pp. 255-264
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T(h)1 but not T(h)0 cell help is efficient to induce cytotoxic T lymphocytes by immunization with short synthetic peptides
International Immunology, Vol. 11, Núm. 12, pp. 2025-2033
1997
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Synthesis and evaluation of new Reissert analogs as HIV-1 RT inhibitors. 2. Benzo[f]quinoline and pyridine derivatives
Drug Design and Discovery, Vol. 14, Núm. 4, pp. 291-303
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Synthesis and evaluation of new Reissert analogs as HIV-1 reverse transcriptase inhibitors. 1. Quinoline and quinoxaline derivatives
Drug Design and Discovery, Vol. 14, Núm. 4, pp. 305-332