(FC) Bioquímica y Genética
Departamento académico
Alfonso
Calvo González
Catedrático de Universidad
Publicaciones en las que colabora con Alfonso Calvo González (21)
2024
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Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation
Molecular Cancer, Vol. 23, Núm. 1
2022
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Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism
Nature medicine, Vol. 28, Núm. 4, pp. 752-765
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Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma
DMM Disease Models and Mechanisms, Vol. 15, Núm. 1
2021
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Molecular biomarkers in early stage lung cancer
Translational Lung Cancer Research, Vol. 10, Núm. 2, pp. 1165-1185
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SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation
Journal for ImmunoTherapy of Cancer, Vol. 9, Núm. 3
2020
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Id1 and pd-1 combined blockade impairs tumor growth and survival of KRAS-mutant lung cancer by stimulating PD-l1 expression and tumor infiltrating CD8+ T cells
Cancers, Vol. 12, Núm. 11, pp. 1-22
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Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade
Nature cancer, Vol. 1, Núm. 1, pp. 75-85
2019
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Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1
Scientific Reports, Vol. 9, Núm. 1
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Identification of mutations associated with acquired resistance to sunitinib in renal cell cancer
International Journal of Cancer, Vol. 145, Núm. 7, pp. 1991-2001
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Targeting of TMPRSS4 sensitizes lung cancer cells to chemotherapy by impairing the proliferation machinery
Cancer Letters, Vol. 453, pp. 21-33
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Tmprss4: A novel tumor prognostic indicator for the stratification of stage ia tumors and a liquid biopsy biomarker for nsclc patients
Journal of Clinical Medicine, Vol. 8, Núm. 12
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YES1 drives lung cancer growth and progression and predicts sensitivity to dasatinib
American Journal of Respiratory and Critical Care Medicine, Vol. 200, Núm. 7, pp. 888-899
2017
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Strategies to design clinical studies to identify predictive biomarkers in cancer research
Cancer Treatment Reviews, Vol. 53, pp. 79-97
2016
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Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients
Oncotarget, Vol. 7, Núm. 16, pp. 22752-22769
2014
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New syngeneic inflammatory-related lung cancer metastatic model harboring double KRAS/WWOX alterations
International Journal of Cancer, Vol. 135, Núm. 11, pp. 2516-2527
2011
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Inhibitor of differentiation-1 as a novel prognostic factor in NSCLC patients with adenocarcinoma histology and its potential contribution to therapy resistance
Clinical Cancer Research, Vol. 17, Núm. 12, pp. 4155-4166
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Overexpression of TMPRSS4 in non-small cell lung cancer is associated with poor prognosis in patients with squamous histology
British Journal of Cancer, Vol. 105, Núm. 10, pp. 1608-1614
2010
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VEGF121b and VEGF165b are weakly angiogenic isoforms of VEGF-A
Molecular Cancer, Vol. 9
2008
2007
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Alternative splicing: an emerging topic in molecular and clinical oncology
Lancet Oncology, Vol. 8, Núm. 4, pp. 349-357