(FC) Bioquímica y Genética
Departamento académico
María Jesús
Perugorria Montiel
Publicaciones en las que colabora con María Jesús Perugorria Montiel (55)
2024
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Fibroblast-Derived Lysyl Oxidase Increases Oxidative Phosphorylation and Stemness in Cholangiocarcinoma
Gastroenterology, Vol. 166, Núm. 5, pp. 886-901.e7
2023
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A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans
Hepatology (Baltimore, Md.), Vol. 78, Núm. 3, pp. 709-726
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Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma
Journal of Hepatology, Vol. 79, Núm. 1, pp. 93-108
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Targeting the Heterogeneous Tumour-Associated Macrophages in Hepatocellular Carcinoma
Cancers, Vol. 15, Núm. 20
2022
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Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids
Hepatology, Vol. 76, Núm. 6, pp. 1617-1633
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Genetics, pathobiology and therapeutic opportunities of polycystic liver disease
Nature Reviews Gastroenterology and Hepatology, Vol. 19, Núm. 9, pp. 585-604
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TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation
Journal of Hepatology, Vol. 77, Núm. 4, pp. 991-1004
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Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models
Journal of Hepatology, Vol. 77, Núm. 1, pp. 177-190
2021
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Anti-miR-518d-5p overcomes liver tumor cell death resistance through mitochondrial activity
Cell Death and Disease, Vol. 12, Núm. 6
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E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment
Cancer Research, Vol. 81, Núm. 11, pp. 2874-2887
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FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted
Journal of Hepatology, Vol. 75, Núm. 2, pp. 363-376
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Inhibition of NAE-dependent protein hyper-NEDDylation in cystic cholangiocytes halts cystogenesis in experimental models of polycystic liver disease
United European Gastroenterology Journal, Vol. 9, Núm. 7, pp. 848-859
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Pathogenesis of Cholangiocarcinoma
Annual Review of Pathology: Mechanisms of Disease, Vol. 16, pp. 433-463
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Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease
Hepatology, Vol. 73, Núm. 1, pp. 186-203
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TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms
Gut, Vol. 70, Núm. 7, pp. 1345-1361
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Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models
Journal of Hepatology, Vol. 74, Núm. 2, pp. 394-406
2020
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Cholangiocarcinoma 2020: the next horizon in mechanisms and management
Nature Reviews Gastroenterology and Hepatology, Vol. 17, Núm. 9, pp. 557-588
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Efficacy and safety of the combination of pravastatin and sorafenib for the treatment of advanced hepatocellular carcinoma (Estahep clinical trial)
Cancers, Vol. 12, Núm. 7, pp. 1-14
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Extracellular vesicles in non-alcoholic fatty liver disease: Key players in disease pathogenesis and promising biomarker tools
NAFLD and NASH: Biomarkers in Detection, Diagnosis and Monitoring (Springer International Publishing), pp. 157-180
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Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis
Cells, Vol. 9, Núm. 3