(FC) Bioquímica y Genética
Departamento académico
Edurne
San José Enériz
Investigadora Asociada
Publicaciones en las que colabora con Edurne San José Enériz (21)
2024
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Epigenetic-based differentiation therapy for Acute Myeloid Leukemia
Nature Communications, Vol. 15, Núm. 1
2019
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Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma
Hepatology, Vol. 69, Núm. 2, pp. 587-603
2018
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Detailed Exploration around 4-Aminoquinolines Chemical Space to Navigate the Lysine Methyltransferase G9a and DNA Methyltransferase Biological Spaces
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6546-6573
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Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6518-6545
2017
2015
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Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers
Genome Research, Vol. 25, Núm. 4, pp. 478-487
2012
2011
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Deregulation of FGFR1 and CDK6 oncogenic pathways in acute lymphoblastic leukaemia harbouring epigenetic modifications of the MIR9 family
British Journal of Haematology, Vol. 155, Núm. 1, pp. 73-83
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Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in Acute Lymphoblastic Leukemia
PLoS ONE, Vol. 6, Núm. 2
2009
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Epigenetic regulation of MicroRNAs in acute lymphoblastic leukemia
Journal of Clinical Oncology, Vol. 27, Núm. 8, pp. 1316-1322
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Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia
Cancer Research, Vol. 69, Núm. 10, pp. 4443-4453
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MicroRNA expression profiling in Imatinib-resistant Chronic Myeloid Leukemia patients without clinically significant ABL1-mutations
Molecular Cancer, Vol. 8, pp. 69
2008
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BCR-ABL1-induced expression of HSPA8 promotes cell survival in chronic myeloid leukaemia
British Journal of Haematology, Vol. 142, Núm. 4, pp. 571-582
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Characterization of the paracrine effects of human skeletal myoblasts transplanted in infarcted myocardium
European Journal of Heart Failure, Vol. 10, Núm. 11, pp. 1065-1072
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Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth
Molecular Cancer Research, Vol. 6, Núm. 12, pp. 1830-1840
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Resistance to Imatinib Mesylate-induced apoptosis in acute lymphoblastic leukemia is associated with PTEN down-regulation due to promoter hypermethylation
Leukemia Research, Vol. 32, Núm. 5, pp. 709-716
2007
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Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia
Blood, Vol. 109, Núm. 8, pp. 3462-3469
2006
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CpG island methylator phenotype redefines the prognostic effect of t(12;21) in childhood acute lymphoblastic leukemia
Clinical Cancer Research, Vol. 12, Núm. 16, pp. 4845-4850
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Downregulation of DBC1 expression in acute lymphoblastic leukaemia is mediated by aberrant methylation of its promoter
British Journal of Haematology, Vol. 134, Núm. 2, pp. 137-144