(FC) Bioquímica y Genética
Departamento académico
Paula
Olaizola Rebe
Publikationen, an denen er mitarbeitet Paula Olaizola Rebe (23)
2023
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A TGFβ-ECM-integrin signaling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease
Science translational medicine, Vol. 15, Núm. 713, pp. eabq5930
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A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans
Hepatology (Baltimore, Md.), Vol. 78, Núm. 3, pp. 709-726
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Aberrant fucosylation sustains the NOTCH and EGFR/NF-κB pathways and has a prognostic value in human intrahepatic cholangiocarcinoma
Hepatology (Baltimore, Md.), Vol. 78, Núm. 6, pp. 1742-1754
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Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma
Journal of Hepatology, Vol. 79, Núm. 1, pp. 93-108
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PFKFB4 Is a Metabolic Driver of HCC Progression and Chemoresistance Through ROS Mitigation
Cellular and Molecular Gastroenterology and Hepatology
2022
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Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids
Hepatology, Vol. 76, Núm. 6, pp. 1617-1633
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Genetics, pathobiology and therapeutic opportunities of polycystic liver disease
Nature Reviews Gastroenterology and Hepatology, Vol. 19, Núm. 9, pp. 585-604
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Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis
Nature Communications, Vol. 13, Núm. 1
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TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation
Journal of Hepatology, Vol. 77, Núm. 4, pp. 991-1004
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Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models
Journal of Hepatology, Vol. 77, Núm. 1, pp. 177-190
2021
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FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted
Journal of Hepatology, Vol. 75, Núm. 2, pp. 363-376
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Inhibition of NAE-dependent protein hyper-NEDDylation in cystic cholangiocytes halts cystogenesis in experimental models of polycystic liver disease
United European Gastroenterology Journal, Vol. 9, Núm. 7, pp. 848-859
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Pathogenesis of Cholangiocarcinoma
Annual Review of Pathology: Mechanisms of Disease, Vol. 16, pp. 433-463
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Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models
Journal of Hepatology, Vol. 74, Núm. 2, pp. 394-406
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Unscrambling a novel pathogenic role for interleukin-20 in acute hepatitis and bacterial infection: A double-edged sword?
Journal of Hepatology
2020
2019
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Antitumor Activity of a Novel Fibroblast Growth Factor Receptor Inhibitor for Intrahepatic Cholangiocarcinoma
American Journal of Pathology, Vol. 189, Núm. 10, pp. 2090-2101
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Cholangiocyte-to-Hepatocyte Differentiation: A Context-Dependent Process and an Opportunity for Regenerative Medicine
Hepatology
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Wnt–β-catenin signalling in liver development, health and disease
Nature Reviews Gastroenterology and Hepatology, Vol. 16, Núm. 2, pp. 121-136
2018
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Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1864, Núm. 4, pp. 1335-1344