Publications en collaboration avec des chercheurs de University of Edinburgh (13)

2023

  1. A TGFβ-ECM-integrin signaling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease

    Science translational medicine, Vol. 15, Núm. 713, pp. eabq5930

  2. A second update on mapping the human genetic architecture of COVID-19

    Nature

  3. Erratum to: Mapping the human genetic architecture of COVID-19 (Nature, (2021), 600, 7889, (472-477), 10.1038/s41586-021-03767-x)

    Nature

2022

  1. Activation of the unfolded protein response (Upr) is associated with cholangiocellular injury, fibrosis and carcinogenesis in an experimental model of fibropolycystic liver disease

    Cancers, Vol. 14, Núm. 1

  2. Clinical relevance of biomarkers in cholangiocarcinoma: critical revision and future directions

    Gut, Vol. 71, Núm. 8, pp. 1669-1683

  3. New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming

    Journal of Experimental and Clinical Cancer Research, Vol. 41, Núm. 1

  4. Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage

    Science translational medicine, Vol. 14, Núm. 674, pp. eabj4375

2021

  1. Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids

    Cell Stem Cell, Vol. 28, Núm. 5, pp. 816-832

  2. Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma

    Hepatology, Vol. 73, Núm. 6, pp. 2380-2396

  3. Mapping the human genetic architecture of COVID-19

    Nature, Vol. 600, Núm. 7889, pp. 472-477

  4. Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility

    PLoS ONE, Vol. 16, Núm. 8

2020

  1. Cholangiocarcinoma 2020: the next horizon in mechanisms and management

    Nature Reviews Gastroenterology and Hepatology, Vol. 17, Núm. 9, pp. 557-588

  2. Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors

    Nature Communications, Vol. 11, Núm. 1