Instituto de Biodiversidad y Medioambiente (BIOMA)
Centro / Instituto de investigación de la Universidad de Navarra
Silvia
Pérez Silanes
Catedrática de Universidad
Publicaciones en las que colabora con Silvia Pérez Silanes (8)
2019
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Rational modification of Mannich base-type derivatives as novel antichagasic compounds: Synthesis, in vitro and in vivo evaluation
Bioorganic and Medicinal Chemistry, Vol. 27, Núm. 17, pp. 3902-3917
2018
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Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi
Journal of Medicinal Chemistry, Vol. 61, Núm. 13, pp. 5643-5663
2017
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Development, validation and application of a GC–MS method for the simultaneous detection and quantification of neutral lipid species in Trypanosoma cruzi
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Vol. 1061-1062, pp. 225-232
2016
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Exploring the scope of new arylamino alcohol derivatives: Synthesis, antimalarial evaluation, toxicological studies, and target exploration
International Journal for Parasitology: Drugs and Drug Resistance, Vol. 6, Núm. 3, pp. 184-198
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In Vitro and in Vivo Anti-Trypanosoma cruzi Activity of New Arylamine Mannich Base-Type Derivatives
Journal of Medicinal Chemistry, Vol. 59, Núm. 24, pp. 10929-10945
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Synthesis and biological evaluation of quinoxaline di-N-oxide derivatives with in vitro trypanocidal activity
Bioorganic and Medicinal Chemistry Letters, Vol. 26, Núm. 3, pp. 903-906
2013
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Novel quinoxaline 1,4-di-N-oxide derivatives as new potential antichagasic agents
European Journal of Medicinal Chemistry, Vol. 66, pp. 324-334
2011
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3-trifluoromethylquinoxaline N, N′-dioxides as anti-Trypanosomatid agents. Identification of optimal anti- T. cruzi agents and mechanism of action studies
Journal of Medicinal Chemistry, Vol. 54, Núm. 10, pp. 3624-3636