Facultad de Medicina (FM)
Centro académico
María Ujué
Latasa Sada
Investigadora Asociada
Publicacións nas que colabora con María Ujué Latasa Sada (61)
2024
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Caspases compromise SLU7 and UPF1 stability and NMD activity during hepatocarcinogenesis
JHEP Reports, Vol. 6, Núm. 8
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Identification of PRMT5 as a therapeutic target in cholangiocarcinoma
Gut
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New insights into the regulation of bile acids synthesis during the early stages of liver regeneration: A human and experimental study
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1870, Núm. 5
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Non-mitogenic FGF19 mRNA-based therapy for the treatment of experimental metabolic dysfunction-associated steatotic liver disease (MASLD)
Clinical science (London, England : 1979), Vol. 138, Núm. 20, pp. 1265-1284
2023
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Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis (Nature Communications, (2019), 10, 1, (3126), 10.1038/s41467-019-11004-3)
Nature Communications
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Comprehensive analysis of epigenetic and epitranscriptomic genes’ expression in human NAFLD
Journal of Physiology and Biochemistry, Vol. 79, Núm. 4, pp. 901-924
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Hepatocyte dedifferentiation profiling in alcohol-related liver disease identifies CXCR4 as a driver of cell reprogramming
Journal of Hepatology, Vol. 79, Núm. 3, pp. 728-740
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Identification and experimental validation of druggable epigenetic targets in hepatoblastoma
Journal of Hepatology, Vol. 79, Núm. 4, pp. 989-1005
2022
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Activation of the unfolded protein response (Upr) is associated with cholangiocellular injury, fibrosis and carcinogenesis in an experimental model of fibropolycystic liver disease
Cancers, Vol. 14, Núm. 1
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New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming
Journal of Experimental and Clinical Cancer Research, Vol. 41, Núm. 1
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Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures
Gut, Vol. 71, Núm. 6, pp. 1141-1151
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Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage
Nature Communications, Vol. 13, Núm. 1
2021
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Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma
Hepatology, Vol. 73, Núm. 6, pp. 2380-2396
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Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: Dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis
Gut, Vol. 70, Núm. 2, pp. 388-400
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Fragile X mental retardation protein in intrahepatic cholangiocarcinoma: regulating the cancer cell behavior plasticity at the leading edge
Oncogene, Vol. 40, Núm. 23, pp. 4033-4049
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The splicing regulator SLU7 is required to preserve DNMT1 protein stability and DNA methylation
Nucleic Acids Research, Vol. 49, Núm. 15, pp. 8592-8609
2020
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Pilot multi-omic analysis of human bile from benign and malignant biliary strictures: A machine-learning approach
Cancers, Vol. 12, Núm. 6, pp. 1-30
2019
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Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis
Nature Communications, Vol. 10, Núm. 1
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Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma
Hepatology, Vol. 69, Núm. 2, pp. 587-603
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Splicing events in the control of genome integrity: Role of SLU7 and truncated SRSF3 proteins
Nucleic Acids Research, Vol. 47, Núm. 7, pp. 3450-3466