Facultad de Medicina (FM)
Centro académico
Maria del Carmen
Ochoa Nieto
Investigadora
Publicacións nas que colabora con Maria del Carmen Ochoa Nieto (69)
2024
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Low-Dose Ionizing γ-Radiation Elicits the Extrusion of Neutrophil Extracellular Traps
Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 30, Núm. 18, pp. 4131-4142
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The oncolytic adenovirus Delta-24-RGD in combination with ONC201 induces a potent antitumor response in pediatric high-grade and diffuse midline glioma models
Neuro-Oncology, Vol. 26, Núm. 8, pp. 1509-1525
2023
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CD137 (4-1BB) requires physically associated cIAPs for signal transduction and antitumor effects
Science advances, Vol. 9, Núm. 33, pp. eadf6692
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Intratumoral co-injection of NK cells and NKG2A-neutralizing monoclonal antibodies
EMBO Molecular Medicine, Vol. 15, Núm. 11
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Intratumoral immunotherapy with mRNAs encoding chimeric protein constructs encompassing IL-12, CD137 agonists, and TGF-β antagonists
Molecular Therapy - Nucleic Acids, Vol. 33, pp. 668-682
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Intratumoral neoadjuvant immunotherapy based on the BO-112 viral RNA mimetic
OncoImmunology, Vol. 12, Núm. 1
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Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma
Cell Reports Medicine, Vol. 4, Núm. 4
2022
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A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα and IL-1β
Cancer Discovery, Vol. 12, Núm. 9, pp. 2140-2157
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Killers on the loose: Immunotherapeutic strategies to improve NK cell-based therapy for cancer treatment
International Review of Cell and Molecular Biology (Elsevier Inc.), pp. 65-122
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Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies
Journal for immunotherapy of cancer, Vol. 10, Núm. 3
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Three-dimensional colon cancer organoids model the response to CEA-CD3 T-cell engagers
Theranostics, Vol. 12, Núm. 3, pp. 1373-1387
2021
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An Fc-free EGFR-specific 4-1BB-agonistic trimerbody displays broad antitumor activity in humanized murine cancer models without toxicity
Clinical Cancer Research, Vol. 27, Núm. 11, pp. 3167-3177
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Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Núm. 26
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CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation
Nature Communications, Vol. 12, Núm. 1
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CD137 Costimulation Counteracts TGFβ Inhibition of NK-cell Antitumor Function
Cancer Immunology Research, Vol. 9, Núm. 12, pp. 1476-1490
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Differential Interleukin-8 thresholds for chemotaxis and netosis in human neutrophils
European Journal of Immunology, Vol. 51, Núm. 9, pp. 2274-2280
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Heterogenous presence of neutrophil extracellular traps in human solid tumours is partially dependent on IL-8
Journal of Pathology, Vol. 255, Núm. 2, pp. 190-201
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IL8, neutrophils, and NETs in a collusion against cancer immunity and immunotherapy
Clinical Cancer Research, Vol. 27, Núm. 9, pp. 2383-2393
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Intratumoral co-injection of the poly I:C-derivative BO-112 and a STING agonist synergize to achieve local and distant anti-tumor efficacy
Journal for ImmunoTherapy of Cancer, Vol. 9, Núm. 11
2020
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CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity
Immunity, Vol. 52, Núm. 5, pp. 856-871.e8