Cancer Center Clínica Universidad de Navarra (CCUN)
Centro clínico de la Universidad de Navarra
María D.
Odero
Investigadora hasta 2024
Publicaciones en las que colabora con María D. Odero (57)
2023
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Activation of the PP2A-B56α heterocomplex synergizes with venetoclax therapies in AML through BCL2 and MCL1 modulation
Blood, Vol. 141, Núm. 9, pp. 1047-1059
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Regulation and role of the PP2A-B56 holoenzyme family in cancer
Biochimica et Biophysica Acta - Reviews on Cancer, Vol. 1878, Núm. 5
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Set Protein Is Involved in FLT3 Membrane Trafficking
Cancers, Vol. 15, Núm. 8
2021
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Endogenous retroelement activation by epigenetic therapy reverses the warburg effect and elicits mitochondrial-mediated cancer cell death
Cancer Discovery, Vol. 11, Núm. 5, pp. 1268-1285
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Tumor cells in light-chain amyloidosis and myeloma show distinct transcriptional rewiring of normal plasma cell development
Blood, Vol. 138, Núm. 17, pp. 1583-1589
2020
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A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia
Blood Cancer Journal, Vol. 10, Núm. 1
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A novel FTY720 analogue targets SET-PP2A interaction and inhibits growth of acute myeloid leukemia cells without inducing cardiac toxicity
Cancer Letters, Vol. 468, pp. 1-13
2017
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MYC-dependent recruitment of RUNX1 and GATA2 on the SET oncogene promoter enhances PP2A inactivation in acute myeloid leukemia
Oncotarget, Vol. 8, Núm. 33, pp. 53989-54003
2016
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Protein phosphatase 2A as a therapeutic target in acute myeloid leukemia
Frontiers in Oncology, Vol. 6, Núm. APR
2015
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CIP2A high expression is a poor prognostic factor in normal karyotype acute myeloid leukemia
Haematologica
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GATA2 germline mutations impair GATA2 transcription, causing haploinsufficiency: Functional analysis of the p.Arg396Gln mutation
Journal of Immunology, Vol. 194, Núm. 5, pp. 2190-2198
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Lipid nanosystems enhance the bioavailability and the therapeutic efficacy of FTY720 in acute myeloid leukemia
Journal of Biomedical Nanotechnology, Vol. 11, Núm. 4, pp. 691-701
2014
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Effect of FTY720 on the SET-PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity
Leukemia
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Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels
Journal of Hematology and Oncology, Vol. 7, Núm. 1
2013
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Edelfosine lipid nanosystems overcome drug resistance in leukemic cell lines
Cancer Letters, Vol. 334, Núm. 2, pp. 302-310
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Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription
Oncogene, Vol. 32, Núm. 16, pp. 2069-2078
2012
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Epigenetic regulation of miRNA genes in acute leukemia
Leukemia, Vol. 26, Núm. 3, pp. 395-403
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Mutation patterns of 16 genes in primary and secondary acute myeloid leukemia (AML) with normal cytogenetics
PLoS ONE, Vol. 7, Núm. 8
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Overexpression of GATA2 predicts an adverse prognosis for patients with acute myeloid leukemia and it is associated with distinct molecular abnormalities
Leukemia
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The role of the GATA2 transcription factor in normal and malignant hematopoiesis
Critical Reviews in Oncology/Hematology, Vol. 82, Núm. 1, pp. 1-17