Tratamiento de los tumores metafiso-epifisarios malignos de extremidad inferior con prótesis

Abstract

From April 1977 to June 1992, 110 case s of malignant bone tumors have been treated in the Department of Orthopaedic s of the Navarra University Clinic by limb salvage surgery located al he femur and tibia epiphysis. The mean follow-up period was 6.4 year s (1 to 15 years). The histologic diagnosis was osteosarcoma in 48 cases, metastasis in 25 cases, Ewing's sarcoma in 8 case s and others. The anatomi c sites included proximal femur in 42 cases and distal femur or proximal tibia in 56 cases. All the patients wer e treated following the Cance r Protocols of the Navarra Universit y Clinic. At review, the global survival rate wa s 72%. 5 case s (8%) developed local recurrences and 5% metastatic disease. The most significant complications wer e infection 6 cases, and failure of the material of osteosynthesis (Knee endoprosthesis) 6 cases. We think that the medical, surgical and rehabilitative advance s have allowed limb saving surger y t o becom e th e primar y metho d o f treatmen t o f bon e malignan t tumor s i n young children, being a successful alternative to amputation.