Síndrome embolia grasa

  1. Laura Noguera Alonso
  2. Irene Ruiz Adelantado
  3. Lorenzo Alarcón García
  4. Clara Sáez Ibarra
Revista:
Revista Sanitaria de Investigación

ISSN: 2660-7085

Año de publicación: 2024

Volumen: 5

Número: 5

Tipo: Artículo

DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Revista Sanitaria de Investigación

Resumen

Fat embolism syndrome (FES), much more common than fat embolism, is developed in male subjects between 20 and 40 years old, who present close long bone fractures. Clinical presentation includes respiratory distress, neurological symptoms and petechial rash 12 to 72 hours after injury. Since there is no direct and proper treatment, prevention is the goal. Besides, novel treatments altering the renin-angiotensin pathway are encouraging. In the trauma field, early stabilization of the fracture must be carried out as soon as possible, unless a group of patients who benefit from control damage and later fixation. Strategies to limit fat embolism are: slow advancement and revolutions of the reamer and RIA system. Routine steroids are not recommended as prophylaxis.

Referencias bibliográficas

  • Commentary on an article by Anna N. Miller, MD et al. . Cerebral fat microembolism and its potential role in postoperative cognitive dysfunction after major orthopaedic surgery. Bone Jt Surg Am 2016;98e33.
  • Pitto RP, Hamer H, Fabiani R, Radespiel- Troeger M KM. Prophylaxis against fat and bone-marrow embolism during total hip arthroplasty reduces the incidence of postoperative deep-vein thrombosis: A controlled, randomized clinical trial. J Bone Jt Surg Am 2002; 84-A39-48.
  • AR: G. Fat embolism: An aid to diagnosis. J Bone Jt Surg Br 1970;52 732-737.
  • King MB HK. Unusual forms of pulmonary embolism. Clin Chest Med 1994;15561-580.
  • Tzioupis CC GP. Fat embolism syndrome: What have we learned over the years? Trauma 2011;13:259-281.
  • Mellor A SN. Fat embolism. Anaesth 2001;56145-154.
  • Prakash S, Sen RK, Tripathy SK, Sen IM, Sharma RR SS. Role of interleukin- 6 as an early marker of fat embolism syndrome: A clinical study. Clin Orthop Relat Res 2013;4712340-2346.
  • Newbigin K, Souza CA, Torres C et al: Fat embolism syndrome: State-of-the-art review focused on pulmonary imaging findings. Respir Med 2016;11393-100.
  • Kuo KH, Pan YJ, Lai YJ, Cheung WK, Chang FC JJ. Dynamic MR imaging patterns of cerebral fat embolism: A systematic review with illustrative cases. AJNR Am J Neuroradiol 2014;35 1052-1057.
  • Fletcher AN, Molteni A, Ponnapureddy R, Patel C, Pluym M PA. The renin inhibitor aliskiren protects rat lungs from the histopathologic effects of fat embolism. J Trauma Acute Care Surg 2017;82 338-344.
  • Sen RK, Tripathy SK KV. Role of corticosteroid as a prophylactic measure in fat embolism syndrome: A literature review. Musculoskelet Surg 2012;961-8.
  • Vallier HA, Moore TA, Como JJ et al: Complications are reduced with a protocol to standardize timing of fixation based on response to resuscitation. J Orthop Surg Res 2015;10155.
  • Bosse MJ, MacKenzie EJ, Riemer BL et al: Adult respiratory distress syndrome, pneumonia, and mortality following thoracic injury and a femoral fracture treated either with intramedullary nailing with reaming or with a plate: A comparative study. J Bone Jt Surg Am 1997;79799-809.
  • Pape HC, Rixen D, Morley J et al: Impact of the method of initial stabilization for femoral shaft fractures in patients with multiple injuries at risk for complications (borderline patients). Ann Surg 2007;246 491-501.
  • S: COT. Reamed versus unreamed intramedullary nailing of the femur: Comparison of the rate of ARDS in multiple injured patients. J Orthop Trauma 2006;20384-38.
  • Mousavi M, David R, Schwendenwein I et al: Influence of controlled reaming on fat intravasation after femoral osteotomy in sheep. Clin Orthop Relat Res 2002 263-270.
  • Miller AN, Deal D, Green J et al: Use of the reamer/irrigator/aspirator decreases carotid and cranial embolic events in a canine model. J Bone Jt Surg Am 2016; 98658-664.
Fuente de los datos: Dialnet