Raw data for "Development and characterization of a non-human primate model of disseminated synucleinopathy"
- Rico, Alberto J. 1
- Corcho, Almudena 2
- Julia, Chocarro 2
- Ariznabarreta, Goiaz 2
- Roda, Elvira 2
- Adriana, Honrubia 2
- Patricia, Arnaiz 2
- Lanciego, Jose L. 3
- 1 CNS Gene Therapy Program, Center for Appplied Medical Research (CIMA), Univiersity of Navarra, Pamplona, Spain
- 2 CNS Gene Therapy Program, Center for Applied Medical Research (CIMA), University of Navarra
- 3 CNS Gene Therapy Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain
Argitaratzaile: Zenodo
Argitalpen urtea: 2023
Mota: Dataset
DOI:
10.5281/ZENODO.10390250
lock_openSarbide irekia editor
Laburpena
In this study, the performance and biodistribution of the retrogradely-spreading AAV9-SynA53T vector was evaluated in the NHP brain. Conducted intraparenchymal deliveries of viral suspensions in the left putamen gave rise to a disseminated synucleinopathy in a circuit-specific basis.