Carmen
Unzu Ezquerro
Profesional Investigadora
Carmen Unzu Ezquerro-rekin lankidetzan egindako argitalpenak (11)
2015
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Helper-dependent adenovirus achieve more efficient and persistent liver transgene expression in non-human primates under immunosuppression
Gene Therapy, Vol. 22, Núm. 11, pp. 856-865
2014
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Innate functions of immunoglobulin M lessen liver gene transfer with helper-dependent adenovirus
PLoS ONE, Vol. 9, Núm. 1
2013
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Helper-dependent adenoviral liver gene therapy protects against induced attacks and corrects protein folding stress in acute intermittent porphyria mice
Human Molecular Genetics, Vol. 22, Núm. 14, pp. 2929-2940
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Safety and liver transduction efficacy of raav5-cohpbgd in nonhuman primates: A potential therapy for acute intermittent porphyria
Human Gene Therapy, Vol. 24, Núm. 12, pp. 1007-1017
2012
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Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse
PLoS ONE, Vol. 7, Núm. 3
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Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates.
Journal of translational medicine, Vol. 10, pp. 122
2011
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Sustained enzymatic correction by rAAV-mediated liver gene therapy protects against induced motor neuropathy in acute porphyria mice
Molecular Therapy, Vol. 19, Núm. 2, pp. 243-250
2010
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Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates
Molecular Therapy, Vol. 18, Núm. 4, pp. 754-765
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Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria
Journal of Hepatology, Vol. 52, Núm. 3, pp. 417-424
2009
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Epidermal growth factor receptor ligands in murine models for erythropoietic protoporphyria: Potential novel players in the progression of liver injury
Cellular and Molecular Biology, Vol. 55, Núm. 1, pp. 29-37