Hepatología: Metabolismo, Epigenética y Carcinogénesis
METACAN
Instituto de Salud Carlos III
Madrid, EspañaPublicacións en colaboración con investigadores/as de Instituto de Salud Carlos III (27)
2024
2023
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Frontiers in fatty liver: recent advances in pathogenic mechanisms, assessment of patients’ prognosis and pharmacotherapy: MASLD: new pathogenic mechanisms, risk assessment tools and drug therapies
Journal of Physiology and Biochemistry
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Loss of liver function in chronic liver disease: An identity crisis
Journal of Hepatology, Vol. 78, Núm. 2, pp. 401-414
2022
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Bile Processing Protocol for Improved Proteomic Analysis
Methods in Molecular Biology (Humana Press Inc.), pp. 1-10
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Immunogenomic classification of hepatocellular carcinoma patients for immune check-point inhibitors therapy: Cui bono ?
Gut
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Impact of CYLD on chromatin structure and histone methylation in malignant melanoma
International Journal of Molecular Medicine, Vol. 49, Núm. 5
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New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming
Journal of Experimental and Clinical Cancer Research, Vol. 41, Núm. 1
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Recombinant porphobilinogen deaminase targeted to the liver corrects enzymopenia in a mouse model of acute intermittent porphyria
Science Translational Medicine, Vol. 14, Núm. 627
2021
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Armcx3 mediates susceptibility to hepatic tumorigenesis promoted by dietary lipotoxicity
Cancers, Vol. 13, Núm. 5, pp. 1-22
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Diagnosis and management of inborn errors of metabolism in adult patients in the emergency department
Diagnostics, Vol. 11, Núm. 11
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Digging deeper into bile proteome
Journal of Proteomics, Vol. 230
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FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted
Journal of Hepatology, Vol. 75, Núm. 2, pp. 363-376
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High prevalence of insulin resistance in asymptomatic patients with acute intermittent porphyria and liver-targeted insulin as a novel therapeutic approach
Biomedicines, Vol. 9, Núm. 3, pp. 1-18
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Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis
Molecular Metabolism, Vol. 53
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The splicing regulator SLU7 is required to preserve DNMT1 protein stability and DNA methylation
Nucleic Acids Research, Vol. 49, Núm. 15, pp. 8592-8609
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mRNA-based therapy in a rabbit model of variegate porphyria offers new insights into the pathogenesis of acute attacks
Molecular Therapy - Nucleic Acids, Vol. 25, pp. 207-219
2019
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Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib
British Journal of Pharmacology, Vol. 176, Núm. 6, pp. 787-800
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Messenger RNA therapy for rare genetic metabolic diseases
Gut, Vol. 68, Núm. 7, pp. 1323-1330
2018
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Fibroblast growth factors 19 and 21 in acute liver damage
Annals of Translational Medicine, Vol. 6, Núm. 12, pp. 257