Publications by the researcher in collaboration with Jesús María Prieto Valtueña (38)

2022

  1. Recombinant porphobilinogen deaminase targeted to the liver corrects enzymopenia in a mouse model of acute intermittent porphyria

    Science Translational Medicine, Vol. 14, Núm. 627

2018

  1. Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications

    Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1864, Núm. 4, pp. 1326-1334

2017

  1. Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice

    Cell Death and Disease, Vol. 8, Núm. 10

  2. Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: Development of an FGF19-based chimeric molecule to promote fatty liver regeneration

    Gut, Vol. 66, Núm. 10, pp. 1818-1828

2016

  1. Interferon alpha bioactivity critically depends on Scavenger receptor class B type I function

    OncoImmunology, Vol. 5, Núm. 8

2015

  1. Chronic exposure to IFNα drives medullar lymphopoiesis towards t-cell differentiation in mice

    Haematologica, Vol. 100, Núm. 8, pp. 1014-1022

  2. Liver-directed gene therapy of chronic hepadnavirus infection using interferon alpha tethered to apolipoprotein A-I

    Journal of Hepatology, Vol. 63, Núm. 2, pp. 329-336

2014

  1. Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases

    PLoS ONE, Vol. 9, Núm. 5

2013

  1. Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein

    Cancer Research, Vol. 73, Núm. 1, pp. 139-149

  2. Cytokines for the treatment of gastrointestinal cancers: Clinical experience and new perspectives

    Expert Opinion on Investigational Drugs, Vol. 22, Núm. 7, pp. 827-841

  3. Eradication of liver-implanted tumors by semliki forest virus expressing IL-12 requires efficient long-term immune responses

    Journal of Immunology, Vol. 190, Núm. 6, pp. 2994-3004

  4. Targeting Interferon-α to the Liver: Apolipoprotein A-I as a Scaffold for Protein Delivery

    Fusion Protein Technologies for Biopharmaceuticals: Applications and Challenges (John Wiley and Sons), pp. 441-452

2012

  1. A Semliki Forest virus vector engineered to express IFNα induces efficient elimination of established tumors

    Gene Therapy, Vol. 19, Núm. 3, pp. 271-278

  2. Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin

    International Journal of Cancer, Vol. 131, Núm. 3, pp. 641-651

  3. Liver Gene Transfer of Interkeukin-15 Constructs That Become Part of Circulating High Density Lipoproteins for Immunotherapy

    PLoS ONE, Vol. 7, Núm. 12

  4. The fusion protein of IFN-α and apolipoprotein A-I crosses the blood-brain barrier by a saturable transport mechanism

    Journal of Immunology, Vol. 188, Núm. 8, pp. 3988-3992

2011

  1. Anchoring interferon alpha to apolipoprotein A-I reduces hematological toxicity while enhancing immunostimulatory properties

    Hepatology, Vol. 53, Núm. 6, pp. 1864-1873

  2. Characterization of woodchuck apolipoprotein A-I: A new tool for drug delivery and identification of altered isoforms in the woodchuck chronic hepatitis model

    Journal of Medical Virology, Vol. 83, Núm. 7, pp. 1221-1229

  3. Development of a liver-specific tet-on inducible system for AAV vectors and its application in the treatment of liver cancer

    Molecular Therapy, Vol. 19, Núm. 7, pp. 1245-1253

  4. Successful colon cancer eradication after chemoimmunotherapy is associated with profound phenotypic change of intratumoral myeloid cells

    Journal of Immunology, Vol. 186, Núm. 2, pp. 807-815