Publicaciones (57) Publicaciones de Mikel Hernaez Arrazola

2024

  1. Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1

    EMBO molecular medicine, Vol. 16, Núm. 1, pp. 112-131

  2. GeNNius: an ultrafast drug-target interaction inference method based on graph neural networks

    Bioinformatics (Oxford, England), Vol. 40, Núm. 1

  3. Genie: the first open-source ISO/IEC encoder for genomic data

    Communications Biology, Vol. 7, Núm. 1

  4. NetActivity enhances transcriptional signals by combining gene expression into robust gene set activity scores through interpretable autoencoders

    Nucleic Acids Research, Vol. 52, Núm. 9, pp. e44

  5. Single-cell transcriptional profile of CD34+ hematopoietic progenitor cells from del(5q) myelodysplastic syndromes and impact of lenalidomide

    Nature Communications, Vol. 15, Núm. 1

  6. Whole exome sequencing and machine learning germline analysis of individuals presenting with extreme phenotypes of high and low risk of developing tobacco-associated lung adenocarcinoma

    eBioMedicine, Vol. 102

2023

  1. Bayesian Machine Learning Enables Identification of Transcriptional Network Disruptions Associated with Drug-Resistant Prostate Cancer

    Cancer research, Vol. 83, Núm. 8, pp. 1361-1380

  2. Identifying key multifunctional components shared by critical cancer and normal liver pathways via SparseGMM

    Cell Reports Methods, Vol. 3, Núm. 1

  3. Microglia and astrocyte activation is region-dependent in the α-synuclein mouse model of Parkinson's disease

    GLIA, Vol. 71, Núm. 3, pp. 571-587

  4. Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia

    Frontiers in Immunology, Vol. 14

  5. Single-cell dissection of aggression in honeybee colonies

    Nature Ecology and Evolution, Vol. 7, Núm. 8, pp. 1232-1244

  6. Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single-cell resolution

    eLife, Vol. 12

2022

  1. CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome

    Science Advances, Vol. 8, Núm. 39

  2. JIND: Joint integration and discrimination for automated single-cell annotation

    Bioinformatics, Vol. 38, Núm. 9, pp. 2488-2495

  3. SimiC enables the inference of complex gene regulatory dynamics across cell phenotypes

    Communications Biology, Vol. 5, Núm. 1

  4. The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes

    Nature Communications, Vol. 13, Núm. 1

2021

  1. An Introduction to MPEG-G: The First Open ISO/IEC Standard for the Compression and Exchange of Genomic Sequencing Data

    Proceedings of the IEEE, Vol. 109, Núm. 9, pp. 1607-1622

  2. Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver

    Genome Research, Vol. 31, Núm. 4, pp. 576-591

  3. Towards scalable genomic data access

    Nature Computational Science

2020

  1. CROMqs: An infinitesimal successive refinement lossy compressor for the quality scores

    Journal of Bioinformatics and Computational Biology, Vol. 18, Núm. 6