Publicaciones (46) Publicaciones de Borja Sáez Ochoa

2023

  1. In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis

    Nature Genetics, Vol. 55, Núm. 9, pp. 1542-1554

2022

  1. Deconvolution of the hematopoietic stem cell microenvironment reveals a high degree of specialization and conservation

    iScience, Vol. 25, Núm. 5

  2. Promises and Challenges of Cell-Based Therapies to Promote Lung Regeneration in Idiopathic Pulmonary Fibrosis

    Cells, Vol. 11, Núm. 16

  3. The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells

    Leukemia, Vol. 36, Núm. 8, pp. 1969-1979

2021

  1. Molecular and Cellular Mechanisms of Delayed Fracture Healing in Mmp10 (Stromelysin 2) Knockout Mice

    Journal of Bone and Mineral Research, Vol. 36, Núm. 11, pp. 2203-2213

  2. Notch3 deficiency attenuates pulmonary fibrosis and impedes lung-function decline

    American Journal of Respiratory Cell and Molecular Biology, Vol. 64, Núm. 4, pp. 465-476

  3. tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche

    Cell Stem Cell, Vol. 28, Núm. 12, pp. 2090-2103.e9

2020

  1. Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers

    Blood, Vol. 136, Núm. 11, pp. 1303-1316

  2. Characterization of freshly isolated mesenchymal stromal cells from healthy and multiple myeloma bone marrow: Transcriptional modulation of the microenvironment.

    Haematologica, Vol. 105, Núm. 5

  3. Engineering a humanised niche to support human haematopoiesis in mice: novel opportunities in modelling cancer

    Cancers, Vol. 12, Núm. 8, pp. 1-23

2019

  1. Role of the Extracellular Matrix in Stem Cell Maintenance

    Current Stem Cell Reports, Vol. 5, Núm. 1

  2. Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation

    Nature Communications, Vol. 10, Núm. 1

2017

  1. Erratum: Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells (Cell (2016) 167(5) (1310–1322.e17)(S0092867416314660)(10.1016/j.cell.2016.10.045)

    Cell

  2. Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1

    Molecular Cell, Vol. 65, Núm. 5, pp. 832-847.e4

  3. Harnessing the Biology of Stem Cells' Niche

    Biology and Engineering of Stem Cell Niches (Elsevier Inc.), pp. 15-31

  4. Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome

    Nature Communications, Vol. 8

  5. Splicing factor gene mutations in hematologic malignancies

    Blood, Vol. 129, Núm. 10, pp. 1260-1269

2016

  1. Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells

    Cell, Vol. 167, Núm. 5, pp. 1310-1322.e17

  2. Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin

    Nature Biotechnology, Vol. 34, Núm. 7, pp. 738-745

  3. Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Núm. 7, pp. 1871-1876