Borja
Sáez Ochoa
Investigador hasta 2022
Publicaciones (46) Publicaciones de Borja Sáez Ochoa
2023
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In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis
Nature Genetics, Vol. 55, Núm. 9, pp. 1542-1554
2022
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Deconvolution of the hematopoietic stem cell microenvironment reveals a high degree of specialization and conservation
iScience, Vol. 25, Núm. 5
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Promises and Challenges of Cell-Based Therapies to Promote Lung Regeneration in Idiopathic Pulmonary Fibrosis
Cells, Vol. 11, Núm. 16
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The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells
Leukemia, Vol. 36, Núm. 8, pp. 1969-1979
2021
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Molecular and Cellular Mechanisms of Delayed Fracture Healing in Mmp10 (Stromelysin 2) Knockout Mice
Journal of Bone and Mineral Research, Vol. 36, Núm. 11, pp. 2203-2213
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Notch3 deficiency attenuates pulmonary fibrosis and impedes lung-function decline
American Journal of Respiratory Cell and Molecular Biology, Vol. 64, Núm. 4, pp. 465-476
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tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche
Cell Stem Cell, Vol. 28, Núm. 12, pp. 2090-2103.e9
2020
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Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers
Blood, Vol. 136, Núm. 11, pp. 1303-1316
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Characterization of freshly isolated mesenchymal stromal cells from healthy and multiple myeloma bone marrow: Transcriptional modulation of the microenvironment.
Haematologica, Vol. 105, Núm. 5
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Engineering a humanised niche to support human haematopoiesis in mice: novel opportunities in modelling cancer
Cancers, Vol. 12, Núm. 8, pp. 1-23
2019
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Role of the Extracellular Matrix in Stem Cell Maintenance
Current Stem Cell Reports, Vol. 5, Núm. 1
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Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation
Nature Communications, Vol. 10, Núm. 1
2017
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Erratum: Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells (Cell (2016) 167(5) (1310–1322.e17)(S0092867416314660)(10.1016/j.cell.2016.10.045)
Cell
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Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
Molecular Cell, Vol. 65, Núm. 5, pp. 832-847.e4
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Harnessing the Biology of Stem Cells' Niche
Biology and Engineering of Stem Cell Niches (Elsevier Inc.), pp. 15-31
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Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome
Nature Communications, Vol. 8
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Splicing factor gene mutations in hematologic malignancies
Blood, Vol. 129, Núm. 10, pp. 1260-1269
2016
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Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells
Cell, Vol. 167, Núm. 5, pp. 1310-1322.e17
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Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin
Nature Biotechnology, Vol. 34, Núm. 7, pp. 738-745
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Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway
Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Núm. 7, pp. 1871-1876