(FM) Medicina Interna
Departamento académico
Manuela
González Aparicio
Investigadora hasta 2023
Publicaciones en las que colabora con Manuela González Aparicio (23)
2024
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Characterization of brain transduction capability of a BBB-penetrant AAV vector in mice, rats and macaques reveals differences in expression profiles
Gene Therapy, Vol. 31, Núm. 9-10, pp. 455-466
2023
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Application of a split-Cre system for high-capacity adenoviral vector amplification
Biotechnology Journal, Vol. 18, Núm. 3
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Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome
Journal of Molecular Medicine, Vol. 101, Núm. 12, pp. 1587-1601
2021
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Adenovirus-mediated inducible expression of a pd-l1 blocking antibody in combination with macrophage depletion improves survival in a mouse model of peritoneal carcinomatosis
International Journal of Molecular Sciences, Vol. 22, Núm. 8
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AdrA as a Potential Immunomodulatory Candidate for STING-Mediated Antiviral Therapy That Required Both Type I IFN and TNF-α Production
Journal of immunology (Baltimore, Md. : 1950), Vol. 206, Núm. 2, pp. 376-385
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Author Correction: Epilepsy and neuropsychiatric comorbidities in mice carrying a recurrent Dravet syndrome SCN1A missense mutation (Scientific Reports, (2019), 9, 1, (14172), 10.1038/s41598-019-50627-w)
Scientific Reports
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Gene supplementation of CYP27A1 in the liver restores bile acid metabolism in a mouse model of cerebrotendinous xanthomatosis
Molecular Therapy - Methods and Clinical Development, Vol. 22, pp. 210-221
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Local administration of IL-12 with an HC vector results in local and metastatic tumor control in pediatric osteosarcoma
Molecular Therapy - Oncolytics, Vol. 20, pp. 23-33
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Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations
Molecular Therapy - Nucleic Acids, Vol. 25, pp. 585-602
2020
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High-capacity adenoviral vectors: Expanding the scope of gene therapy
International Journal of Molecular Sciences, Vol. 21, Núm. 10
2019
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Danio rerio as model organism for adenoviral vector evaluation
Genes, Vol. 10, Núm. 12
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Epilepsy and neuropsychiatric comorbidities in mice carrying a recurrent Dravet syndrome SCN1A missense mutation
Scientific Reports, Vol. 9, Núm. 1
2018
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Inhibition of adenovirus infection by mifepristone
Antiviral Research, Vol. 159, pp. 77-83
2017
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Adaptation of vectors and drug-inducible systems for controlled expression of transgenes in the tumor microenvironment
Journal of Controlled Release, Vol. 268, pp. 247-258
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X-box Binding Protein 1 Regulates Unfolded Protein, Acute-Phase, and DNA Damage Responses During Regeneration of Mouse Liver
Gastroenterology, Vol. 152, Núm. 5, pp. 1203-1216.e15
2015
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Enhanced therapeutic effect using sequential administration of antigenically distinct oncolytic viruses expressing oncostatin M in a Syrian hamster orthotopic pancreatic cancer model
Molecular Cancer, Vol. 14, Núm. 1
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Safety and antitumor effect of oncolytic and helper-dependent adenoviruses expressing interleukin-12 variants in a hamster pancreatic cancer model
Gene Therapy, Vol. 22, Núm. 9, pp. 696-706
2013
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Helper-dependent adenoviral liver gene therapy protects against induced attacks and corrects protein folding stress in acute intermittent porphyria mice
Human Molecular Genetics, Vol. 22, Núm. 14, pp. 2929-2940
2012
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Modulation of regulatory T-cell activity in combination with interleukin-12 increases hepatic tolerogenicity in woodchucks with chronic hepatitis B
Hepatology, Vol. 56, Núm. 2, pp. 474-483
2011
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Nuevo protocolo de producción de adenovirus de alta capacidad basado en un adenovirus helper auto-inactivable
Nuevo protocolo de producción de adenovirus de alta capacidad basado en un adenovirus helper auto-inactivable